Huang Yung-Jui, Jiann Bang-Ping
Department of Surgery, Kaohsiung Veterans General Hospital and Graduate School of Human Sexuality, Shu-Te University, Kaohsiung, Taiwan.
Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung and School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Sex Med. 2017 Sep;5(3):e163-e168. doi: 10.1016/j.esxm.2017.05.002. Epub 2017 Aug 1.
Areca nut chewing has been shown to increase the risk of cardiovascular disease, but its association with erectile dysfunction (ED) has not been investigated.
To investigate the association between areca nut chewing and risk of ED.
Consecutive men at public health centers for oral malignancy screening or health checkup were invited to complete a questionnaire.
The Sexual Health Inventory for Men (SHIM).
Of the 2,652 respondents, 1,038 (mean age = 43.8 ± 11.1 years) were eligible for the areca nut chewing group and 1,090 non-areca nut chewers were selected as the age-matched control group. In the areca nut group, the mean duration of chewing was 13.2 ± 9.6 years, 61.7% consumed more than 10 portions per day, and 76.2% used it with betel leaf, 16.7% used it with betel inflorescence, and 7.1% used it with betel leaf and inflorescence. Smoking, alcohol drinking, obesity, hypertension, and diabetes were more predominant in areca nut chewers compared with controls. ED defined by self-report and by SHIM score was more prevalent in areca nut chewers than in controls (13.7% vs 9.8% and 48.7% vs 43.3%, respectively; P < .05 for the two comparisons). Areca nut use with betel inflorescence was associated with a higher risk of ED (odds ratio = 2.25, 95% confidence interval = 1.55-3.28) with a dose-dependent effect, whereas using it with betel leaf was not (odds ratio = 1.00, 95% confidence interval = 0.79-1.26) after adjustment of possible confounders.
Areca nut chewing with betel inflorescence was associated with an increased risk of ED. These findings warrant further studies. Huang Y-J, Jiann B-P. Association of Areca Nut Chewing With Risk of Erectile Dysfunction. Sex Med 2017;5:e163-e168.
嚼槟榔已被证明会增加心血管疾病风险，但其与勃起功能障碍（ED）的关联尚未得到研究。
研究嚼槟榔与勃起功能障碍风险之间的关联。
邀请在公共卫生中心进行口腔恶性肿瘤筛查或健康检查的连续男性完成一份问卷。
男性性健康量表（SHIM）。
在2652名受访者中，1038名（平均年龄 = 43.8 ± 11.1岁）符合嚼槟榔组条件，1090名不嚼槟榔者被选为年龄匹配的对照组。在槟榔组中，平均咀嚼时间为13.2 ± 9.6年，61.7%的人每天食用超过10份，76.2%的人搭配荖叶食用，16.7%的人搭配槟榔花食用，7.1%的人搭配荖叶和槟榔花食用。与对照组相比，嚼槟榔者中吸烟、饮酒、肥胖、高血压和糖尿病更为常见。通过自我报告和SHIM评分定义的勃起功能障碍在嚼槟榔者中比对照组更普遍（分别为13.7%对9.8%和48.7%对43.3%；两项比较P < 0.05）。在调整可能混杂因素后，搭配槟榔花食用槟榔与更高的勃起功能障碍风险相关（比值比 = 2.25，95%置信区间 = 1.55 - 3.28），具有剂量依赖性效应，而搭配荖叶食用则不然（比值比 = 1.00，95%置信区间 = 0.79 - 1.26）。
搭配槟榔花嚼槟榔与勃起功能障碍风险增加有关。这些发现值得进一步研究。黄Y-J，简B-P。嚼槟榔与勃起功能障碍风险的关联。性医学2017；5：e163 - e168。
