过度训练综合征的激素方面：一项系统综述。
Hormonal aspects of overtraining syndrome: a systematic review.
作者信息
Cadegiani Flavio A, Kater Claudio E
机构信息
Adrenal and Hypertension Unit, Division of Endocrinology and Metabolism, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM/UNIFESP), R. Pedro de Toledo 781 - 13th floor, São Paulo, SP 04039-032 Brazil.
出版信息
BMC Sports Sci Med Rehabil. 2017 Aug 2;9:14. doi: 10.1186/s13102-017-0079-8. eCollection 2017.
BACKGROUND
Overtraining syndrome (OTS), functional (FOR) and non-functional overreaching (NFOR) are conditions diagnosed in athletes with decreased performance and fatigue, triggered by metabolic, immune, hormonal and other dysfunctions and resulted from an imbalance between training stress and proper recovery. Despite previous descriptions, there is a lack of a review that discloses all hormonal findings in OTS/FOR/NFOR. The aim of this systematic review is to evaluate whether and which roles hormones play in OTS/FOR/NFOR.
METHODS
A systematic search up to June 15, 2017 was performed in the PUBMED, MEDLINE and Cochrane databases following PRISMA protocol, with the expressions: (1)overtraining, (2)overreaching, (3)overtrained, (4)overreached, or (5)underperformance, and (plus) (a)hormone, (b)hormonal, (c)endocrine, (d)adrenal, (e)cortisol, (f)GH, (g)ACTH, (h)testosterone, (i)IGF-1, (j)TSH, (k)T4, (l)T3, (m)LH, (n)FSH, (o)prolactin, (p) IGFBP-3 and related articles.
RESULTS
A total of 38 studies were selected. Basal levels of hormones were mostly normal in athletes with OTS/FOR/NFOR compared with healthy athletes. Distinctly, stimulation tests, mainly performed in maximal exercise conditions, showed blunted GH and ACTH responses in OTS/FOR/NFOR athletes, whereas cortisol and plasma catecholamines showed conflicting findings and the other hormones responded normally.
CONCLUSION
Basal hormone levels are not good predictor but blunted ACTH and GH responses to stimulation tests may be good predictors of OTS/FOR/NFOR.
背景
过度训练综合征（OTS）、功能性过度训练（FOR）和非功能性过度训练（NFOR）是在运动员中诊断出的状况，表现为成绩下降和疲劳，由代谢、免疫、激素及其他功能障碍引发，是训练压力与适当恢复之间失衡的结果。尽管此前已有相关描述，但缺乏一项全面揭示OTS/FOR/NFOR中所有激素研究结果的综述。本系统综述的目的是评估激素在OTS/FOR/NFOR中是否发挥作用以及发挥何种作用。
方法
按照PRISMA方案，于2017年6月15日前在PUBMED、MEDLINE和Cochrane数据库中进行系统检索，检索词如下：（1）过度训练，（2）过度训练期，（3）过度训练的，（4）处于过度训练期的，（5）表现不佳，以及（加）（a）激素，（b）激素的，（c）内分泌的，（d）肾上腺的，（e）皮质醇，（f）生长激素（GH），（g）促肾上腺皮质激素（ACTH），（h）睾酮，（i）胰岛素样生长因子-1（IGF-1），（j）促甲状腺激素（TSH），（k）甲状腺素（T4），（l）三碘甲状腺原氨酸（T3），（m）促黄体生成素（LH），（n）促卵泡生成素（FSH），（o）催乳素，（p）胰岛素样生长因子结合蛋白-3（IGFBP-3）及相关文章。
结果
共筛选出38项研究。与健康运动员相比，OTS/FOR/NFOR运动员的基础激素水平大多正常。明显的是，主要在最大运动条件下进行的刺激试验显示，OTS/FOR/NFOR运动员的GH和ACTH反应减弱，而皮质醇和血浆儿茶酚胺的结果相互矛盾，其他激素反应正常。
结论
基础激素水平并非良好的预测指标，但ACTH和GH对刺激试验的反应减弱可能是OTS/FOR/NFOR的良好预测指标。
Zotero 插件