细菌和古菌单扩增基因组（MISAG）及宏基因组组装基因组（MIMAG）的最低信息要求
Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea.
作者信息
Bowers Robert M, Kyrpides Nikos C, Stepanauskas Ramunas, Harmon-Smith Miranda, Doud Devin, Reddy T B K, Schulz Frederik, Jarett Jessica, Rivers Adam R, Eloe-Fadrosh Emiley A, Tringe Susannah G, Ivanova Natalia N, Copeland Alex, Clum Alicia, Becraft Eric D, Malmstrom Rex R, Birren Bruce, Podar Mircea, Bork Peer, Weinstock George M, Garrity George M, Dodsworth Jeremy A, Yooseph Shibu, Sutton Granger, Glöckner Frank O, Gilbert Jack A, Nelson William C, Hallam Steven J, Jungbluth Sean P, Ettema Thijs J G, Tighe Scott, Konstantinidis Konstantinos T, Liu Wen-Tso, Baker Brett J, Rattei Thomas, Eisen Jonathan A, Hedlund Brian, McMahon Katherine D, Fierer Noah, Knight Rob, Finn Rob, Cochrane Guy, Karsch-Mizrachi Ilene, Tyson Gene W, Rinke Christian, Lapidus Alla, Meyer Folker, Yilmaz Pelin, Parks Donovan H, Eren A M, Schriml Lynn, Banfield Jillian F, Hugenholtz Philip, Woyke Tanja
机构信息
Department of Energy Joint Genome Institute, Walnut Creek, California, USA.
Bigelow Laboratory for Ocean Sciences, East Boothbay, Maine, USA.
出版信息
Nat Biotechnol. 2017 Aug 8;35(8):725-731. doi: 10.1038/nbt.3893.
We present two standards developed by the Genomic Standards Consortium (GSC) for reporting bacterial and archaeal genome sequences. Both are extensions of the Minimum Information about Any (x) Sequence (MIxS). The standards are the Minimum Information about a Single Amplified Genome (MISAG) and the Minimum Information about a Metagenome-Assembled Genome (MIMAG), including, but not limited to, assembly quality, and estimates of genome completeness and contamination. These standards can be used in combination with other GSC checklists, including the Minimum Information about a Genome Sequence (MIGS), Minimum Information about a Metagenomic Sequence (MIMS), and Minimum Information about a Marker Gene Sequence (MIMARKS). Community-wide adoption of MISAG and MIMAG will facilitate more robust comparative genomic analyses of bacterial and archaeal diversity.
我们展示了由基因组标准联盟（GSC）制定的两个用于报告细菌和古菌基因组序列的标准。这两个标准都是“关于任何（x）序列的最小信息”（MIxS）的扩展。这两个标准分别是“关于单个扩增基因组的最小信息”（MISAG）和“关于宏基因组组装基因组的最小信息”（MIMAG），包括但不限于组装质量，以及基因组完整性和污染程度的估计。这些标准可与其他GSC清单结合使用，包括“关于基因组序列的最小信息”（MIGS）、“关于宏基因组序列的最小信息”（MIMS）和“关于标记基因序列的最小信息”（MIMARKS）。全社区采用MISAG和MIMAG将有助于对细菌和古菌多样性进行更可靠的比较基因组分析。
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