Department of Psychiatry, Medical University of Warsaw, 27 Nowowiejska str, 00-665, Warsaw, Poland.
1st Department of Obstetrics and Gynaecology, Medical University of Warsaw, Warsaw, Poland.
Metab Brain Dis. 2017 Dec;32(6):1913-1918. doi: 10.1007/s11011-017-0079-0. Epub 2017 Aug 8.
After childbirth, women may develop symptoms of depression with the associated sleep disturbances. This study assessed the relationship between insomnia and both depression symptoms and blood estradiol levels in women during the early postpartum period. 84 patients were assessed 24-48 h after labor. The main assessment methods were the following psychometric scales: Beck Depression Inventory (BDI), Edinburgh Postnatal Depression Scale (EPDS) and Athens Insomnia Scale (AIS). Serum estradiol levels were measured using ELISA assay. Women who developed postpartum insomnia significantly more often reported insomnia during pregnancy (P = 0.001), were more likely to have suffered from depression in the past (P = 0.007) and had significantly higher BDI (P = 0.002) and EPDS (P = 0.048) scores. Our study demonstrated no significant association between Restless Legs Syndrome (RLS) during pregnancy and postpartum insomnia. The groups of women with and without postpartum RLS showed no significant differences in the incidence of postpartum insomnia. No significant differences in estradiol levels were observed in women with and without postpartum insomnia. The study showed the following factors to play a major role in development of postpartum insomnia: an increase in Beck Depression Inventory score, a history of depression and a history of insomnia during pregnancy.
产后，女性可能会出现抑郁症状，并伴有相关的睡眠障碍。本研究评估了产后早期女性失眠与抑郁症状和血液雌二醇水平之间的关系。84 名患者在分娩后 24-48 小时进行评估。主要评估方法如下：贝克抑郁量表（BDI）、爱丁堡产后抑郁量表（EPDS）和雅典失眠量表（AIS）。采用 ELISA 法测定血清雌二醇水平。患有产后失眠的女性在怀孕期间更经常报告失眠（P=0.001），过去更有可能患有抑郁症（P=0.007），BDI（P=0.002）和 EPDS（P=0.048）评分明显更高。我们的研究表明，怀孕期间不安腿综合征（RLS）与产后失眠之间没有显著关联。有和没有产后 RLS 的女性中，产后失眠的发生率没有显著差异。产后失眠组和无产后失眠组的雌二醇水平无显著差异。该研究表明，以下因素在产后失眠的发展中起主要作用：贝克抑郁量表评分升高、抑郁史和怀孕期间失眠史。
