Jurczyk Karolina, Miklaszewski Andrzej, Jurczyk Mieczyslawa U, Jurczyk Mieczyslaw
Department of Conservative Dentistry and Periodontology, Poznan University of Medical Sciences, Bukowska 70, Poznan 60-812, Poland.
Institute of Materials Science and Engineering, Poznan University of Technology, Jana Pawla II 24, Poznan 61-138, Poland.
Materials (Basel). 2015 Nov 25;8(12):8032-8046. doi: 10.3390/ma8125441.
Titanium β-type alloys attract attention as biomaterials for dental applications. The aim of this work was the synthesis of nanostructured β type Ti23Mo- wt % 45S5 Bioglass ( = 0, 3 and 10) composites by mechanical alloying and powder metallurgy methods and their characterization. The crystallization of the amorphous material upon annealing led to the formation of a nanostructured β type Ti23Mo alloy with a grain size of approximately 40 nm. With the increase of the 45S5 Bioglass contents in Ti23Mo, nanocomposite increase of the α-phase is noticeable. The electrochemical treatment in phosphoric acid electrolyte resulted in a porous surface, followed by bioactive ceramic Ca-P deposition. Corrosion resistance potentiodynamic testing in Ringer solution at 37 °C showed a positive effect of porosity and Ca-P deposition on nanostructured Ti23Mo 3 wt % 45S5 Bioglass nanocomposite. The contact angles of glycerol on the nanostructured Ti23Mo alloy were determined and show visible decrease for bulk Ti23Mo 3 wt % 45S5 Bioglass and etched Ti23Mo 3 wt % 45S5 Bioglass nanocomposites. tests culture of normal human osteoblast cells showed very good cell proliferation, colonization, and multilayering. The present study demonstrated that porous Ti23Mo 3 wt % 45S5 Bioglass nanocomposite is a promising biomaterial for bone tissue engineering.
钛β型合金作为牙科应用的生物材料受到关注。本工作的目的是通过机械合金化和粉末冶金方法合成纳米结构的β型Ti23Mo - wt% 45S5生物玻璃（ = 0、3和10）复合材料并对其进行表征。退火时非晶材料的结晶导致形成了晶粒尺寸约为40 nm的纳米结构β型Ti23Mo合金。随着Ti23Mo中45S5生物玻璃含量的增加，α相的纳米复合材料增加明显。在磷酸电解质中进行电化学处理产生了多孔表面，随后是生物活性陶瓷Ca - P沉积。在37°C的林格溶液中进行的耐腐蚀动电位测试表明，孔隙率和Ca - P沉积对纳米结构的Ti23Mo 3 wt% 45S5生物玻璃纳米复合材料有积极影响。测定了甘油在纳米结构Ti23Mo合金上的接触角，结果表明块状Ti23Mo 3 wt% 45S5生物玻璃和蚀刻后的Ti23Mo 3 wt% 45S5生物玻璃纳米复合材料的接触角明显减小。正常人成骨细胞的测试培养显示出非常良好的细胞增殖、定植和多层化。本研究表明，多孔Ti23Mo 3 wt% 45S5生物玻璃纳米复合材料是一种有前途的骨组织工程生物材料。
