Jheeta Seetal, Franklin Bryony Dean
Centre for Medication Safety and Service Quality, Imperial College Healthcare NHS Trust, London, UK.
Research Department of Practice and Policy, UCL School of Pharmacy, London, UK.
BMC Health Serv Res. 2017 Aug 9;17(1):547. doi: 10.1186/s12913-017-2462-2.
The aim of the study was to explore the impact of the implementation of an electronic prescribing and medication administration system (ePA) on the safety of medication administration in an inpatient hospital setting. Objectives were to compare the prevalence and types of: 1) medication administration errors, and 2) documentation discrepancies, between a paper and an ePA system. Additionally, we wanted to describe any observed changes to medication administration practices.
The study was based on an elderly medicine ward in an English hospital. From December 2014 to June 2015, nurses' medication administration rounds were observed every 5 days before and after ePA implementation using an interrupted time-series approach. Medication administration error and documentation discrepancy rates pre- versus post-ePA were analysed descriptively and chi-squared tests used to test for any difference; segmented regression analysis was used to determine changes in longitudinal trend.
Observations were made at 15 pre- and 15 post-ePA implementation time-points. Pre-ePA on paper, there were 18 medication administration errors in 428 opportunities for error (4.2%; 95% confidence interval 2.3-6.1%), and with ePA there were 18 in 528 (3.4%; 95% confidence interval 1.9-5.0%; p = 0.64). Regarding documentation, pre-ePA on paper there were 5 discrepancies in 460 observed documentations (1.1%; 95% confidence interval 0.1-2.0%); with ePA there were 18 in 557 (3.2%; 95% confidence interval 1.8-4.7%; p = 0.04). The most common electronic documentation discrepancy was documentation that a dose had been administered when it had not. Segmented regression analysis was unable to detect any significant longitudinal changes. Changes to working practices post-ePA were observed, such as nurses demonstrating less-consistent self-checking when preparing and administering medications.
Findings suggest no change in medication error rate, although ePA encourages certain types of errors and mitigates others. There was a statistically significant increase in documentation discrepancies which is likely to be due to adoption of new working practices with ePA.
本研究的目的是探讨实施电子处方与用药管理系统(ePA)对住院医院环境中用药安全的影响。目标是比较纸质系统和ePA系统之间:1)用药错误;2)记录差异的发生率和类型。此外,我们还想描述观察到的用药管理实践的任何变化。
该研究基于英国一家医院的老年医学科病房。在2014年12月至2015年6月期间,采用间断时间序列方法,在实施ePA前后每5天观察护士的用药巡视情况。对ePA实施前后的用药错误率和记录差异率进行描述性分析,并使用卡方检验来检验是否存在差异;采用分段回归分析来确定纵向趋势的变化。
在实施ePA前和后分别观察了15个时间点。在纸质系统ePA实施前,428次出错机会中有18次用药错误(4.2%;95%置信区间2.3 - 6.1%),在ePA系统下,528次中有18次(3.4%;95%置信区间1.9 - 5.0%;p = 0.64)。关于记录,纸质系统ePA实施前在460次观察记录中有5次差异(1.1%;95%置信区间0.1 - 2.0%);在ePA系统下,557次中有18次(3.2%;95%置信区间1.8 - 4.7%;p = 0.04)。最常见的电子记录差异是记录了未给药的剂量。分段回归分析未能检测到任何显著的纵向变化。观察到实施ePA后工作实践的变化,例如护士在准备和给药时自我检查的一致性降低。
研究结果表明用药错误率没有变化,尽管ePA会引发某些类型的错误,同时也减轻了其他一些错误。记录差异在统计学上有显著增加,这可能是由于采用了ePA的新工作实践所致。