Kaur Kanwalpreet, Gupta Karuna, Hemrajani Deepika, Yadav Ajay, Mangal Kalpana
Department of Pathology, SawaiMan Singh Medical College, Jaipur, Rajasthan, India.
Indian J Dermatol. 2017 Jul-Aug;62(4):400-406. doi: 10.4103/ijd.IJD_380_16.
Skin adnexal tumors (SAT) encompass wide spectrum of benign and malignant tumors that differentiate toward one or more adnexal structures found in normal skin. Overall incidence of SATs is low yet they can be challenging to diagnose.
The aim of this study is to study the spectrum and microscopic features of SATs.
It was a retrospective cross-sectional, descriptive study conducted over a period of 3 years. Formalin fixed, paraffin-embedded sections were stained with hematoxylin and eosin for histopathological analysis.
Out of the total 34,400 biopsies, 110 cases were diagnosed as SATs comprising 39.09% of tumors with follicular differentiation followed by tumors showing sweat gland differentiation (37.27%), and sebaceous differentiation (23.63%). The age ranged from 5 years to 85 years and male:female ratio was 1.03:1. Most of the tumors were benign (82.73%) while only 17.27% were malignant. Pilomatricoma (28.2%) was the most common benign tumor while sebaceous carcinoma (11.8%) was the most common malignant tumor.
Architectural features are of great importance in differentiating benign tumors from malignant.
皮肤附属器肿瘤（SAT）涵盖了广泛的良性和恶性肿瘤，这些肿瘤向正常皮肤中发现的一种或多种附属器结构分化。SAT的总体发病率较低，但诊断可能具有挑战性。
本研究的目的是研究SAT的谱系和微观特征。
这是一项为期3年的回顾性横断面描述性研究。用苏木精和伊红对福尔马林固定、石蜡包埋的切片进行染色，以进行组织病理学分析。
在总共34400例活检中，110例被诊断为SAT，其中39.09%的肿瘤具有毛囊分化，其次是汗腺分化肿瘤（37.27%）和皮脂腺分化肿瘤（23.63%）。年龄范围为5岁至85岁，男女比例为1.03:1。大多数肿瘤为良性（82.73%），而恶性肿瘤仅占17.27%。毛母质瘤（28.2%）是最常见的良性肿瘤，皮脂腺癌（11.8%）是最常见的恶性肿瘤。
结构特征在区分良性肿瘤和恶性肿瘤方面非常重要。
