Smith Mallory K, Nicholson Cynthia L, Parks-Miller Angela, Hamzavi Iltefat H
Wayne State University School of Medicine, Detroit, MI, USA.
Henry Ford Hospital Department of Dermatology, Detroit, MI, USA.
F1000Res. 2017 Jul 28;6:1272. doi: 10.12688/f1000research.11337.1. eCollection 2017.
Hidradenitis suppurativa (HS) is a devastating disease involving abscesses, sinus tracts, and inflammation classically affecting the axilla, groin, and/or anogenital region. Although the disease pathogenesis is not fully understood, recent advances suggest that HS pathology runs much deeper than the cutaneous manifestations. It is now believed that HS is a systemic inflammatory disease that gives rise to the characteristic cutaneous manifestations. This disease is problematic for both patients and physicians to manage because of a variety of diagnostic and management difficulties. This article seeks to provide updates on the current understanding of HS to increase awareness and improve management.
化脓性汗腺炎(HS)是一种破坏性疾病,涉及脓肿、窦道和炎症,典型地影响腋窝、腹股沟和/或肛门生殖器区域。尽管该病的发病机制尚未完全明确,但最近的研究进展表明,HS的病理过程远比皮肤表现更为复杂。目前认为,HS是一种全身性炎症性疾病,可导致特征性的皮肤表现。由于存在各种诊断和管理困难,这种疾病对患者和医生来说都很难处理。本文旨在提供关于HS当前认识的最新信息,以提高认识并改善管理。