Raveendran Sreejith, Rochani Ankit K, Maekawa Toru, Kumar D Sakthi
Bio Nano Electronics Research Centre, Graduate School of Interdisciplinary New Science, Toyo University, Saitama 350-8585, Japan.
Materials (Basel). 2017 Aug 10;10(8):929. doi: 10.3390/ma10080929.
Biodegradable polymers are popularly being used in an increasing number of fields in the past few decades. The popularity and favorability of these materials are due to their remarkable properties, enabling a wide range of applications and market requirements to be met. Polymer biodegradable systems are a promising arena of research for targeted and site-specific controlled drug delivery, for developing artificial limbs, 3D porous scaffolds for cellular regeneration or tissue engineering and biosensing applications. Several natural polymers have been identified, blended, functionalized and applied for designing nanoscaffolds and drug carriers as a prerequisite for enumerable bionano technological applications. Apart from these, natural polymers have been well studied and are widely used in material science and industrial fields. The present review explains the prominent features of commonly used natural polymers (polysaccharides and proteins) in various nanomedical applications and reveals the current status of the polymer research in bionanotechnology and science sectors.
在过去几十年中，可生物降解聚合物在越来越多的领域得到广泛应用。这些材料之所以受欢迎且备受青睐，是因为它们具有卓越的性能，能够满足广泛的应用和市场需求。聚合物可生物降解系统是一个充满前景的研究领域，可用于靶向和位点特异性控释药物、开发人造肢体、用于细胞再生或组织工程的三维多孔支架以及生物传感应用。已经鉴定出几种天然聚合物，将它们进行混合、功能化，并应用于设计纳米支架和药物载体，这是众多生物纳米技术应用的前提条件。除此之外，天然聚合物已经得到深入研究，并广泛应用于材料科学和工业领域。本综述阐述了常用天然聚合物（多糖和蛋白质）在各种纳米医学应用中的突出特点，并揭示了聚合物在生物纳米技术和科学领域的研究现状。
