• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Reply to Silburt et al.: Concerning sterile inflammation following focused ultrasound and microbubbles in the brain.对西尔伯特等人的回复：关于聚焦超声和微泡在大脑中引发的无菌性炎症
Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):E6737-E6738. doi: 10.1073/pnas.1711544114. Epub 2017 Aug 10.
2
Reply to Kovacs .: Concerning acute inflammatory response following focused ultrasound and microbubbles in the brain.回复科瓦奇：关于聚焦超声和微泡在脑部引起的急性炎症反应。
Theranostics. 2018 Mar 8;8(8):2249-2250. doi: 10.7150/thno.25468. eCollection 2018.
3
Focused ultrasound with microbubbles induces sterile inflammatory response proportional to the blood brain barrier opening: Attention to experimental conditions.聚焦超声联合微泡可诱导与血脑屏障开放程度成正比的无菌性炎症反应：关注实验条件。
Theranostics. 2018 Mar 8;8(8):2245-2248. doi: 10.7150/thno.24181. eCollection 2018.
4
A sterile animal model for neuroinflammation?神经炎症的无菌动物模型？
Sci Transl Med. 2017 Jan 18;9(373). doi: 10.1126/scitranslmed.aal4994.
5
Microbubble contrast agent with focused ultrasound to create brain lesions at low power levels: MR imaging and histologic study in rabbits.微泡造影剂联合聚焦超声在低功率水平下造成兔脑损伤：磁共振成像及组织学研究
Radiology. 2006 Oct;241(1):95-106. doi: 10.1148/radiol.2411051170.
6
Ultrasound, microbubbles and the blood-brain barrier.超声、微泡与血脑屏障
Prog Biophys Mol Biol. 2007 Jan-Apr;93(1-3):354-62. doi: 10.1016/j.pbiomolbio.2006.07.019. Epub 2006 Aug 4.
7
Nanoparticle delivery to the brain--By focused ultrasound and self-assembled nanoparticle-stabilized microbubbles.纳米颗粒递送至脑部——通过聚焦超声和自组装纳米颗粒稳定的微泡。
J Control Release. 2015 Dec 28;220(Pt A):287-294. doi: 10.1016/j.jconrel.2015.10.047. Epub 2015 Oct 28.
8
Non-Invasive, Focal Disconnection of Brain Circuitry Using Magnetic Resonance-Guided Low-Intensity Focused Ultrasound to Deliver a Neurotoxin.使用磁共振引导的低强度聚焦超声递送神经毒素对脑回路进行非侵入性、局灶性切断
Ultrasound Med Biol. 2016 Sep;42(9):2261-9. doi: 10.1016/j.ultrasmedbio.2016.04.019. Epub 2016 May 31.
9
Microbubble-Assisted Ultrasound for Drug Delivery in the Brain and Central Nervous System.微泡辅助超声用于脑和中枢神经系统的药物递送
Adv Exp Med Biol. 2016;880:293-308. doi: 10.1007/978-3-319-22536-4_16.
10
[Effect of low-dose focused ultrasound pre-irradiation versus microbubbles for enhancing high-intensity focused ultrasound ablation of VX hepatic tumor in rabbits].[低剂量聚焦超声预照射与微泡对增强兔VX肝肿瘤高强度聚焦超声消融的作用]
Nan Fang Yi Ke Da Xue Xue Bao. 2016 Oct 20;36(10):1352-1356.

引用本文的文献

1
BBB opening by low pulsed electric fields, depicted by delayed-contrast MRI, enables efficient delivery of therapeutic doxorubicin doses into mice brains.低频脉冲电场致 BBB 开放，通过延迟对比 MRI 显示，可提高阿霉素向小鼠脑内的递送效率。
Fluids Barriers CNS. 2023 Sep 22;20(1):67. doi: 10.1186/s12987-023-00468-7.
2
Transcriptomic response of brain tissue to focused ultrasound-mediated blood-brain barrier disruption depends strongly on anesthesia.脑组织对聚焦超声介导的血脑屏障破坏的转录组学反应在很大程度上取决于麻醉。
Bioeng Transl Med. 2020 Nov 24;6(2):e10198. doi: 10.1002/btm2.10198. eCollection 2021 May.
3
Diffusion Tensor Imaging and Chemical Exchange Saturation Transfer MRI Evaluation on the Long-Term Effects of Pulsed Focused Ultrasound and Microbubbles Blood Brain Barrier Opening in the Rat.扩散张量成像和化学交换饱和转移磁共振成像评估脉冲聚焦超声和微泡打开大鼠血脑屏障的长期效应
Front Neurosci. 2020 Aug 25;14:908. doi: 10.3389/fnins.2020.00908. eCollection 2020.
4
Secondary effects on brain physiology caused by focused ultrasound-mediated disruption of the blood-brain barrier.聚焦超声破坏血脑屏障引起的脑生理学的继发效应。
J Control Release. 2020 Aug 10;324:450-459. doi: 10.1016/j.jconrel.2020.05.040. Epub 2020 May 26.
5
Ultrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery.用于治疗和药物递送的超声响应性空化核
Ultrasound Med Biol. 2020 Jun;46(6):1296-1325. doi: 10.1016/j.ultrasmedbio.2020.01.002. Epub 2020 Mar 10.
6
Investigating the effects of dexamethasone on blood-brain barrier permeability and inflammatory response following focused ultrasound and microbubble exposure.研究地塞米松对聚焦超声和微泡暴露后血脑屏障通透性和炎症反应的影响。
Theranostics. 2020 Jan 1;10(4):1604-1618. doi: 10.7150/thno.40908. eCollection 2020.
7
In vivo imaging of sterile microglial activation in rat brain after disrupting the blood-brain barrier with pulsed focused ultrasound: [18F]DPA-714 PET study.在活体大鼠脑中，采用脉冲聚焦超声破坏血脑屏障后，无菌性小胶质细胞激活的体内成像：[18F]DPA-714 PET 研究。
J Neuroinflammation. 2019 Jul 25;16(1):155. doi: 10.1186/s12974-019-1543-z.
8
Reverse engineering the ultrasound contrast agent.超声造影剂的反向工程。
Adv Colloid Interface Sci. 2018 Dec;262:39-49. doi: 10.1016/j.cis.2018.10.004. Epub 2018 Oct 24.
9
MRI and histological evaluation of pulsed focused ultrasound and microbubbles treatment effects in the brain.磁共振成像和组织学评估脉冲聚焦超声及微泡处理对大脑的影响。
Theranostics. 2018 Sep 9;8(17):4837-4855. doi: 10.7150/thno.24512. eCollection 2018.
10
State-of-the-art of microbubble-assisted blood-brain barrier disruption.微泡辅助血脑屏障破坏的最新进展。
Theranostics. 2018 Aug 7;8(16):4393-4408. doi: 10.7150/thno.26869. eCollection 2018.

本文引用的文献

1
Disrupting the blood-brain barrier with focused ultrasound: Perspectives on inflammation and regeneration.聚焦超声破坏血脑屏障：关于炎症与再生的观点
Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):E6735-E6736. doi: 10.1073/pnas.1710761114. Epub 2017 Aug 10.
2
Acute effects of focused ultrasound-induced increases in blood-brain barrier permeability on rat microvascular transcriptome.聚焦超声诱导的血脑屏障通透性增加对大鼠微血管转录组的急性影响。
Sci Rep. 2017 Apr 4;7:45657. doi: 10.1038/srep45657.
3
A sterile animal model for neuroinflammation?神经炎症的无菌动物模型？
Sci Transl Med. 2017 Jan 18;9(373). doi: 10.1126/scitranslmed.aal4994.
4
Disrupting the blood-brain barrier by focused ultrasound induces sterile inflammation.聚焦超声破坏血脑屏障会引发无菌性炎症。
Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):E75-E84. doi: 10.1073/pnas.1614777114. Epub 2016 Dec 19.
5
The Effects of Oxygen on Ultrasound-Induced Blood-Brain Barrier Disruption in Mice.氧气对小鼠超声诱导的血脑屏障破坏的影响。
Ultrasound Med Biol. 2017 Feb;43(2):469-475. doi: 10.1016/j.ultrasmedbio.2016.09.019. Epub 2016 Oct 24.
6
The effect of inhaled gases on ultrasound contrast agent longevity in vivo.吸入气体对体内超声造影剂寿命的影响。
Mol Imaging Biol. 2012 Feb;14(1):40-6. doi: 10.1007/s11307-011-0475-5.
7
Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury.血脑屏障破坏作为创伤性脑损伤的治疗靶点。
Nat Rev Neurol. 2010 Jul;6(7):393-403. doi: 10.1038/nrneurol.2010.74. Epub 2010 Jun 15.
8
Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption.声学参数及超声造影剂剂量对聚焦超声诱导血脑屏障破坏的影响
Ultrasound Med Biol. 2008 Jun;34(6):930-7. doi: 10.1016/j.ultrasmedbio.2007.11.009. Epub 2008 Feb 21.
9
Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound.使用磁共振成像（MRI）引导的聚焦超声将阿霉素以治疗水平靶向递送至大鼠脑部。
Int J Cancer. 2007 Aug 15;121(4):901-7. doi: 10.1002/ijc.22732.
10
Multiphoton imaging of ultrasound/Optison mediated cerebrovascular effects in vivo.超声/Optison介导的脑血管效应的体内多光子成像
J Cereb Blood Flow Metab. 2007 Feb;27(2):393-403. doi: 10.1038/sj.jcbfm.9600336. Epub 2006 May 10.

Reply to Silburt et al.: Concerning sterile inflammation following focused ultrasound and microbubbles in the brain.

作者信息

Kovacs Zsofia I, Burks Scott R, Frank Joseph A

机构信息

Frank Laboratory, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD 20892;

Frank Laboratory, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD 20892.

出版信息

Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):E6737-E6738. doi: 10.1073/pnas.1711544114. Epub 2017 Aug 10.

DOI:10.1073/pnas.1711544114
PMID:28798066
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5565475/
Abstract
摘要