State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
The United States Pharmacopeial Convention, Rockville, MD, USA.
Sci Rep. 2017 Aug 10;7(1):7792. doi: 10.1038/s41598-017-06336-3.
Ganoderma lucidum is a well-known medicinal mushroom. At present, numerous G. lucidum products have emerged in the form of dietary supplements in the United States due to its various benefits. However, the quality consistency of these products based on their label ingredients has seldom been evaluated due to the lack of a suitable toolkit. In this study, 19 batches of products of G. lucidum (Red Reishi, Reishi), herbal/mushroom supplements purchased in the United States, were evaluated based on their bioactive components including triterpenes and polysaccharides by using chromatographic methods and saccharide mapping. The results showed that the measured ingredients of only 5 tested samples (26.3%) were in accordance with their labels, which suggested the quality consistency of G. lucidum dietary supplements in the U.S. market was poor, which should be carefully investigated.
灵芝是一种广为人知的药用蘑菇。由于其具有多种益处，目前在美国，大量的灵芝产品以膳食补充剂的形式出现。然而，由于缺乏合适的工具包，基于标签成分的这些产品的质量一致性很少得到评估。在这项研究中，通过使用色谱方法和糖谱分析，对在美国购买的 19 批灵芝（红灵芝、灵芝）产品进行了评估，这些产品是基于其包括三萜类化合物和多糖在内的生物活性成分。结果表明，只有 5 个测试样品（26.3%）的测量成分与标签相符，这表明美国市场上灵芝膳食补充剂的质量一致性较差，应仔细调查。
