Chikazawa Seishiro, Hoshi Fumio, Kanai Kazutaka
Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University, 23-35-1 Higashi, Towada, Aomori 034-8628, Japan.
J Vet Med Sci. 2017 Oct 7;79(10):1652-1655. doi: 10.1292/jvms.17-0118. Epub 2017 Aug 11.
The aim of the present study was to determine changes in body iron storage in adult dogs following phlebotomy. We performed repeated phlebotomies by removing 1% body weight (approximately 10% of the total blood volume) weekly for a total of 12 times using adult beagle dogs without an iron-restricted diet. After treatment, stored iron was decreased, as demonstrated by gradual reductions in serum ferritin levels and hepatic iron contents. Anemia and abnormalities in blood chemistry analysis were not observed; therefore, this method was considered safe and useful for control of stored iron levels in adult dogs.
本研究的目的是确定成年犬放血后体内铁储存的变化。我们使用未进行铁限制饮食的成年比格犬,每周通过放血去除1%体重(约占总血容量的10%),共进行12次放血。治疗后,储存铁减少,血清铁蛋白水平和肝脏铁含量逐渐降低证明了这一点。未观察到贫血和血液化学分析异常;因此,该方法被认为对控制成年犬的储存铁水平安全且有用。