Hagovska Magdalena, Nagyova Iveta
Department of Physiatry, Balneology, and Medical Rehabilitation, Faculty of Medicine, PJ Safarik University, Rastislavova 43, 040 01 Kosice, Slovak Republic.
Department of Social and Behavioural Medicine, Faculty of Medicine, PJ Safarik University, Kosice, Slovak Republic.
Eur J Ageing. 2016 Sep 3;14(2):133-142. doi: 10.1007/s10433-016-0395-y. eCollection 2017 Jun.
Ageing is associated with the deterioration of all cognitive functions, including attention, memory and psychomotor speed. It has not yet been clearly confirmed whether the effects of cognitive and physical interventions can improve activities of daily living (ADL). This study compared the effectiveness of cognitive and physical training on cognitive functions and the transfer to ADL. Eighty older people with mild cognitive impairment (mean age 67.07 ± 4.3 years) were randomly divided into an experimental group ( = 40) and a control group ( = 40). Data were collected in an outpatient psychiatric clinic in a randomised controlled trial. Primary outcome measures included the following: cognitive functions were evaluated using the mini mental state examination, the AVLT-Auditory verbal learning test, the Stroop test, the TMT-trail making test, the DRT-disjunctive reaction time and the NHPT-nine hole peg test. Secondary outcome measure was the Bristol activities of daily living scale. The experimental group underwent a CogniPlus and physical training; consisting of 20 training sessions over 10 weeks. Both groups went through 30 min of daily physical training for 10 weeks. After the training, significant differences in favour of the experimental group were found in almost all the tests. In memory (AVLT) (p ≤ 0.0001, effect size (ES) = 0.218. In reduction of the response time on attention tasks (Stroop tasks) ( ≤ 0.006, ES = 0.092-0.115). In lower error rates in all tests: Stroop tasks, DRT, TMT, NHPT ( ≤ 0.02-0.001, ES = 0.062-0.176). In ADL ( ≤ 0.0001, ES = 0.176). The combined cognitive and physical training had better efficacy for most cognitive functions and for ADL when compared with the physical training only.
衰老与所有认知功能的衰退有关,包括注意力、记忆力和精神运动速度。认知和身体干预的效果是否能改善日常生活活动(ADL),目前尚未得到明确证实。本研究比较了认知训练和身体训练对认知功能的有效性以及向ADL的转化情况。80名轻度认知障碍的老年人(平均年龄67.07±4.3岁)被随机分为实验组(n = 40)和对照组(n = 40)。在一家门诊精神科诊所进行随机对照试验并收集数据。主要结局指标包括:使用简易精神状态检查表、听觉词语学习测试(AVLT)、斯特鲁普测试、连线测试(TMT)、析取反应时测试(DRT)和九孔插板测试(NHPT)评估认知功能。次要结局指标是布里斯托日常生活活动量表。实验组接受了CogniPlus和身体训练;包括在10周内进行20次训练课程。两组均在10周内每天进行30分钟的身体训练。训练后,几乎所有测试中均发现有利于实验组的显著差异。在记忆力(AVLT)方面(p≤0.0001,效应量(ES)= 0.218)。在注意力任务(斯特鲁普任务)中反应时间缩短方面(p≤0.006,ES = 0.092 - 0.115)。在所有测试(斯特鲁普任务、DRT、TMT、NHPT)中错误率降低方面(p≤0.02 - 0.001,ES = 0.062 - 0.176)。在ADL方面(p≤0.0001,ES = 0.176)。与仅进行身体训练相比,认知训练与身体训练相结合对大多数认知功能和ADL具有更好的疗效。