Morillas E, Gómez-Chacón B, Gallo M
Department of Psychobiology, Institute of Neurosciences, Centre for Biomedical Research (CIBM), University of Granada, Campus Cartuja, Granada 18071, Spain.
Department of Psychobiology, Institute of Neurosciences, Centre for Biomedical Research (CIBM), University of Granada, Campus Cartuja, Granada 18071, Spain.
Neurobiol Learn Mem. 2017 Oct;144:230-234. doi: 10.1016/j.nlm.2017.08.002. Epub 2017 Aug 12.
Recognition memory is based on the ability to assess the familiarity of a previously encountered stimulus. It can be approached using tests for different sensorial modalities. Excitotoxic lesions of the perirhinal cortex (Prh) were performed in order to assess the relevance of its integrity for object and flavor recognition memory. Object recognition memory was impaired with a 24h retention interval. Flavor neophobia attenuation was prevented on a second encounter with the tastant. These results support a role of the perirhinal cortex in mediating the transition from novel to familiar, both in object and flavor recognition memory.
识别记忆基于评估先前遇到的刺激的熟悉程度的能力。它可以通过针对不同感官模态的测试来进行研究。为了评估其完整性对物体和味道识别记忆的相关性，对嗅周皮质（Prh）进行了兴奋性毒性损伤。在24小时的保持间隔下，物体识别记忆受损。在第二次接触味觉刺激时，味道新恐惧症的减轻受到了抑制。这些结果支持嗅周皮质在介导物体和味道识别记忆中从新异到熟悉的转变过程中发挥作用。
