Reddy Paidi Ramakrishna, Thomas Sujith M, Rajalakshmi A, Vijayan Deepak, Raman Muraleedharan
Department of Critical Care, Kerala Institute of Medical Sciences, Thiruvananthapuram, Kerala, India.
Department of Internal Medicine, Division of Infectious Disease, Kerala Institute of Medical Sciences, Thiruvananthapuram, Kerala, India.
Indian J Crit Care Med. 2017 Jul;21(7):466-468. doi: 10.4103/ijccm.IJCCM_139_17.
infection can range from asymptomatic eosinophilia to disseminated disease. Common in tropical and subtropical nations, it can lead to hyperinfection, an autoinfection increasing parasitic burden in immunocompromised. Cell-mediated immunity is important in combating parasite infection. We present a case of hyperinfection in hypogammaglobulinemia which was refractory to conventional treatment but responded to immunoglobulin administration with complete resolution indicating role of humoral immunity also.
感染范围可从无症状嗜酸性粒细胞增多到播散性疾病。该病在热带和亚热带国家很常见,可导致超感染,即一种自身感染,会增加免疫功能低下者体内的寄生虫负担。细胞介导的免疫在对抗寄生虫感染中很重要。我们报告一例低丙种球蛋白血症患者发生超感染的病例,该患者对传统治疗无效,但静脉注射免疫球蛋白后症状完全缓解,这也表明了体液免疫的作用。