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Comparative analysis of essential oil composition of Iranian and Indian L. extracted using supercritical fluid extraction and solvent extraction.

作者信息

Ghahramanloo Kourosh Hasanzadeh, Kamalidehghan Behnam, Akbari Javar Hamid, Teguh Widodo Riyanto, Majidzadeh Keivan, Noordin Mohamed Ibrahim

机构信息

Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Medical Genetics Department, National Institute of Genetic Engineering and Biotechnology (NIGEB).

出版信息

Drug Des Devel Ther. 2017 Jul 28;11:2221-2226. doi: 10.2147/DDDT.S87251. eCollection 2017.

DOI:10.2147/DDDT.S87251
PMID:28814830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5546729/
Abstract

The objective of this study was to compare the oil extraction yield and essential oil composition of Indian and Iranian L. extracted by using Supercritical Fluid Extraction (SFE) and solvent extraction methods. In this study, a gas chromatography equipped with a mass spectrophotometer detector was employed for qualitative analysis of the essential oil composition of Indian and Iranian L. The results indicated that the main fatty acid composition identified in the essential oils extracted by using SFE and solvent extraction were linoleic acid (22.4%-61.85%) and oleic acid (1.64%-18.97%). Thymoquinone (0.72%-21.03%) was found to be the major volatile compound in the extracted oil. It was observed that the oil extraction efficiency obtained from SFE was significantly (<0.05) higher than that achieved by the solvent extraction technique. The present study showed that SFE can be used as a more efficient technique for extraction of L. essential oil, which is composed of higher linoleic acid and thymoquinone contents compared to the essential oil obtained by the solvent extraction technique.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e67/5546729/24b465c7637d/dddt-11-2221Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e67/5546729/5597452b9b88/dddt-11-2221Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e67/5546729/70bea1a83663/dddt-11-2221Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e67/5546729/ae5939f33aed/dddt-11-2221Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e67/5546729/24b465c7637d/dddt-11-2221Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e67/5546729/5597452b9b88/dddt-11-2221Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e67/5546729/70bea1a83663/dddt-11-2221Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e67/5546729/ae5939f33aed/dddt-11-2221Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e67/5546729/24b465c7637d/dddt-11-2221Fig4.jpg

相似文献

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Comparative analysis of essential oil composition of Iranian and Indian L. extracted using supercritical fluid extraction and solvent extraction.

Drug Des Devel Ther. 2017-7-28

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本文引用的文献

[1]
A randomised controlled trial on hypolipidemic effects of Nigella Sativa seeds powder in menopausal women.

J Transl Med. 2014-3-31

[2]
Thymoquinone induces apoptosis in oral cancer cells through p38β inhibition.

Am J Chin Med. 2013

[3]
Methanolic extract of Nigella sativa seed inhibits SiHa human cervical cancer cell proliferation through apoptosis.

Nat Prod Commun. 2013-2

[4]
Effect of dexamethasone and Nigella sativa on peripheral blood eosinophil count, IgG1 and IgG2a, cytokine profiles and lung inflammation in murine model of allergic asthma.

Egypt J Immunol. 2005

[5]
Antidermatophyte activity of ether extract of Nigella sativa and its active principle, thymoquinone.

J Ethnopharmacol. 2005-10-3

[6]
Anticonvulsant effects of thymoquinone, the major constituent of Nigella sativa seeds, in mice.

Phytomedicine. 2004-1

[7]
Chemical composition of the fixed and volatile oils of Nigella sativa L. from Iran.

Z Naturforsch C J Biosci. 2003

[8]
The effect of Nigella sativa oil against the liver damage induced by Schistosoma mansoni infection in mice.

J Ethnopharmacol. 2002-1

[9]
[Diuretic and hypotensive effects of Nigella sativa in the spontaneously hypertensive rat].

Therapie. 2000

[10]
Effects of Nigella sativa oil on gastric secretion and ethanol induced ulcer in rats.

J Ethnopharmacol. 2000-9

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