Ciesielska-Figlon Klaudia, Wojciechowicz Karolina, Wardowska Anna, Lisowska Katarzyna Aleksandra
Department of Physiopathology, Faculty of Medicine, Medical University of Gdańsk, 80-210 Gdańsk, Poland.
Antioxidants (Basel). 2023 Jun 24;12(7):1340. doi: 10.3390/antiox12071340.
For thousands of years till nowadays, (NS) has served as a common spice and food preservative. Its seed extracts, seed oil, and essential oil in traditional medicine have been used to remedy many ailments such as headaches, fever, gastric complaints, and even rheumatism. In addition, the antibacterial, virucidal, fungicidal, and antiparasitic properties of NS are well known. However, studies on the possible immunomodulatory effects of black cumin are relatively scarce. This article discusses in vitro and in vivo research supporting the immunomodulatory role of NS.
The review is based on articles, books, and conference papers printed until September 2022, found in the Web of Science, PubMed, Wiley Online Library, and Google Scholar databases.
Experimental findings were reported concerning the ability of NS to modulate inflammation and immune responses or cytotoxic activity.
All results suggest that NS can potentially be employed in developing effective therapeutic agents for regulating immune reactions.
数千年来直至如今，黑孜然一直作为一种常见的香料和食品防腐剂。其种子提取物、种子油以及传统医学中的精油已被用于治疗多种疾病，如头痛、发烧、胃部不适，甚至风湿。此外，黑孜然的抗菌、抗病毒、杀菌和抗寄生虫特性广为人知。然而，关于黑孜然可能的免疫调节作用的研究相对较少。本文讨论了支持黑孜然免疫调节作用的体外和体内研究。
本综述基于截至2022年9月发表的文章、书籍和会议论文，这些文献来自科学网、PubMed、威利在线图书馆和谷歌学术数据库。
报告了有关黑孜然调节炎症、免疫反应或细胞毒性活性能力的实验结果。
所有结果表明，黑孜然有可能被用于开发调节免疫反应的有效治疗药物。
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