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Definitive chemoradiotherapy.根治性放化疗
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本文引用的文献

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Concurrent cisplatin and 5-fluorouracil versus concurrent cisplatin and docetaxel with radiotherapy for esophageal squamous cell carcinoma: a propensity score-matched analysis.顺铂与5-氟尿嘧啶同步放化疗对比顺铂与多西他赛同步放化疗治疗食管鳞状细胞癌：一项倾向评分匹配分析
Oncotarget. 2016 Jul 12;7(28):44686-44694. doi: 10.18632/oncotarget.9301.
2
Cervical esophageal cancer: a gap in cancer knowledge.颈段食管癌：癌症知识的空白。
Ann Oncol. 2016 Sep;27(9):1664-74. doi: 10.1093/annonc/mdw183. Epub 2016 Apr 26.
3
Non-surgical versus surgical treatment for oesophageal cancer.食管癌的非手术治疗与手术治疗
Cochrane Database Syst Rev. 2016 Mar 29;3(3):CD011498. doi: 10.1002/14651858.CD011498.pub2.
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Radiation dose escalation by simultaneous modulated accelerated radiotherapy combined with chemotherapy for esophageal cancer: a phase II study.同步调强加速放疗联合化疗用于食管癌的放射剂量递增：一项II期研究
Oncotarget. 2016 Apr 19;7(16):22711-9. doi: 10.18632/oncotarget.8050.
5
Impact of Treatment Modalities on Survival of Patients With Locoregional Esophageal Squamous-Cell Carcinoma in Taiwan.治疗方式对台湾局部区域食管癌鳞状细胞癌患者生存率的影响
Medicine (Baltimore). 2016 Mar;95(10):e3018. doi: 10.1097/MD.0000000000003018.
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[Not Available].[无可用内容]。
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7
Variations among 5 European countries for curative treatment of resectable oesophageal and gastric cancer: A survey from the EURECCA Upper GI Group (EUropean REgistration of Cancer CAre).欧洲五个国家可切除食管癌和胃癌根治性治疗的差异：来自EURECCA上消化道组（欧洲癌症护理登记处）的一项调查。
Eur J Surg Oncol. 2016 Jan;42(1):116-22. doi: 10.1016/j.ejso.2015.09.017. Epub 2015 Sep 30.
8
High-dose versus conventional-dose irradiation in cisplatin-based definitive concurrent chemoradiotherapy for esophageal cancer: a systematic review and pooled analysis.基于顺铂的食管癌根治性同步放化疗中高剂量与常规剂量放疗的系统评价与汇总分析
Expert Rev Anticancer Ther. 2015;15(10):1157-69. doi: 10.1586/14737140.2015.1074041. Epub 2015 Aug 3.
9
Is dose escalation achievable for esophageal carcinoma?食管癌的剂量递增是否可行？
Rep Pract Oncol Radiother. 2015 Jan 5;20(2):135-40. doi: 10.1016/j.rpor.2014.12.006. eCollection 2015 Mar-Apr.
10
Randomized phase 2 trial of S1 and oxaliplatin-based chemoradiotherapy with or without induction chemotherapy for esophageal cancer.S1联合奥沙利铂同步放化疗联合或不联合诱导化疗用于食管癌的随机2期试验
Int J Radiat Oncol Biol Phys. 2015 Mar 1;91(3):489-96. doi: 10.1016/j.ijrobp.2014.11.019. Epub 2015 Jan 30.

根治性放化疗

Definitive chemoradiotherapy.

作者信息

Stahl Michael, Budach Wilfried

机构信息

Klinik für Internistische Onkologie und Hämatologie mit integrierter Palliativmedizin, Kliniken Essen-Mitte, Essen, Germany.

Klinik und Poliklinik für Strahlentherapie und Radioonkologie, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.

出版信息

J Thorac Dis. 2017 Jul;9(Suppl 8):S792-S798. doi: 10.21037/jtd.2017.05.05.

DOI:10.21037/jtd.2017.05.05
PMID:28815076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5538992/
Abstract

Definitive chemoradiotherapy (dCRT) is reflecting a treatment standard in oesophageal cancer. For irresectable localised tumours and for inoperable patients, dCRT can change the treatment intent from palliative to curative. In patients with squamous cell carcinoma (SCC), in particular in those of cervical location, dCRT is a proper alternative for treatment that may include radical surgery. Patients with localised locoregional recurrence after primary surgery can survive for long-term after salvage CRT.

摘要

根治性放化疗（dCRT）是食管癌的一种治疗标准。对于无法切除的局部肿瘤和无法手术的患者，dCRT可将治疗目的从姑息性转变为根治性。在鳞状细胞癌（SCC）患者中，尤其是宫颈部位的患者，dCRT是一种合适的治疗选择，其治疗可能包括根治性手术。初次手术后局部区域复发的患者在挽救性放化疗后可长期存活。