Couvé-Deacon E, Postil D, Barraud O, Duchiron C, Chainier D, Labrunie A, Pestourie N, Preux P M, François B, Ploy M C
University Limoges, UMR, 1092, Limoges, France.
INSERM, UMR, 1092, Limoges, France.
Sports Med Open. 2017 Aug 16;3(1):28. doi: 10.1186/s40798-017-0094-z.
Staphylococcus aureus (SA) is a leading cause of infectious diseases in sports teams. In recent decades, community-associated SA (CA-SA) strains have emerged worldwide and have been responsible for outbreaks in sports teams. There are very few data on the prevalence of these strains in France, and none on the carriage among athletes.
We conducted a cross-sectional study to determine the SA carriage proportion among athletes practicing sports at risk for CA-SA infection in a French county, and determined the methicillin-resistant and/or CA-SA proportion. We also analyzed SA carriage according to risks factors and studied the SA clonality in a sample of our population.
We included 300 athletes; SA carriage proportion was 61% (n = 183) and one was MRSA carrier (0.33%). The MRSA strain belonged to the clonal complex ST5. None of the strain produced Panton Valentine Leucocidin, and we did not find clonal distribution within the teams. Interestingly, we found a high throat-only carriage (n = 57), 31.1% of the SA carriers.
We found a high SA carriage with a local epidemiology quite different than that reported in a similar population in the USA. Further studies on SA carriage should include throat sampling.
The approved protocol was registered on ClinicalTrial.gov , NCT01148485.
金黄色葡萄球菌（SA）是运动队感染性疾病的主要病因。近几十年来，社区相关SA（CA-SA）菌株在全球范围内出现，并导致了运动队中的疫情爆发。在法国，关于这些菌株流行率的数据非常少，关于运动员携带情况的数据则完全没有。
我们进行了一项横断面研究，以确定法国一个县中从事有CA-SA感染风险运动的运动员中SA携带比例，并确定耐甲氧西林和/或CA-SA比例。我们还根据风险因素分析了SA携带情况，并在我们的人群样本中研究了SA的克隆性。
我们纳入了300名运动员；SA携带比例为61%（n = 183），1名是耐甲氧西林金黄色葡萄球菌携带者（0.33%）。耐甲氧西林金黄色葡萄球菌菌株属于克隆复合体ST5。没有菌株产生杀白细胞素，并且我们在各团队中未发现克隆分布。有趣的是，我们发现仅咽部携带率很高（n = 57），占SA携带者的31.1%。
我们发现SA携带率很高，其局部流行病学情况与美国类似人群中报告的情况有很大不同。关于SA携带情况的进一步研究应包括咽部采样。
批准的方案已在ClinicalTrial.gov上注册，NCT01148485。
