GENZ-Group of Research on Enzymology, Department of Biochemistry and Molecular Biology-A, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, 30100 Murcia, Spain.
Novozymes Spain S.A., 28224 Madrid, Spain.
Molecules. 2017 Aug 21;22(8):1382. doi: 10.3390/molecules22081382.
The current study describes the composition of (Vahl) essential oils (SlEOs) obtained from plants cultivated in Murcia (Spain), as determined by gas chromatography. Relative and absolute concentrations, the enantiomeric ratios of chiral compounds and the in vitro antioxidant, antienzymatic and antimicrobial activities are described. The main components of the SlEOs were camphor, 1,8-cineole, camphene and α-pinene, and the main enantiomers were (+)-camphor and (-)-camphene. The activities against free radicals and the capacity to reduce and chelate metallic ions were measured. SlEO-3 showed the highest activity in ORAC, DPPH, ABTS and reducing power methods, while SlEO-1 exhibited the highest chelating power. The activity of lipoxygenase and acetylcholinesterase could be inhibited by all the SlEOs, being bornyl acetate and limonene the most active individual compounds against lipoxygenase and 1,8-cineole against acetylcholinesterase. SlEOs and some individual compounds inhibited , and . These results increase our knowledge of SlEOs and, particularly, provide for the first time a complete characterization of SlEOs from Murcia, Spain, while proposing possible biotechnological uses for them.
本研究描述了从西班牙穆尔西亚种植的植物中获得的 (Vahl) 精油（SlEOs）的组成，这是通过气相色谱法确定的。描述了相对和绝对浓度、手性化合物的对映体比例以及体外抗氧化、抗酶和抗菌活性。SlEOs 的主要成分是樟脑、1,8-桉叶油醇、莰烯和α-蒎烯，主要对映体是（+）-樟脑和（-）-莰烯。自由基清除活性以及还原和螯合金属离子的能力均进行了测量。SlEO-3 在 ORAC、DPPH、ABTS 和还原力方法中表现出最高的活性，而 SlEO-1 表现出最高的螯合能力。所有的 SlEOs 都能抑制脂氧合酶和乙酰胆碱酯酶的活性，其中乙酸龙脑酯和柠檬烯是对脂氧合酶最有效的单一化合物，而 1,8-桉叶油醇是对乙酰胆碱酯酶最有效的单一化合物。SlEOs 和一些单一化合物抑制 、 和 。这些结果增加了我们对 SlEOs 的了解，特别是首次提供了来自西班牙穆尔西亚的 SlEOs 的完整特征描述，并提出了它们可能的生物技术用途。
