Jdey A, Falleh H, Ben Jannet S, Mkadmini Hammi K, Dauvergne X, Magné C, Ksouri R
Faculty of Sciences at Bizerte, 7021 Zarzouna, Tunisia.
Laboratory of Aromatic and Medicinal Plants, Centre for Biotechnologies, Technopôle of Borj-Cédria, BP 901, 2050 Hammam-Lif, Tunisia.
EXCLI J. 2017 May 22;16:755-769. doi: 10.17179/excli2017-244. eCollection 2017.
Six medicinal halophytes widely represented in North Africa and commonly used in traditional medicine were screened for pharmacological properties to set out new promising sources of natural ingredients for cosmetic or nutraceutical applications. Thus, , , , , and were examined for their antioxidant (DPPH scavenging and superoxide anion-scavenging, -carotene bleaching inhibition and iron-reducing tests), antibacterial (microdilution method, against four human pathogenic bacteria) and anti-tyrosinase activities. Besides, their aromatic composition was determined by RP-HPLC. shoot extracts exhibited the strongest antioxidant activity and inhibited efficiently the growth of and . and inhibited slightly monophenolase, whereas was the most efficient inhibitor of diphenolase activity. Furthermore, exhibited the highest aromatic content (3.4 % DW), with dopamine as the major compound. These observations suggest that shoot extract of , and to a lesser extent of , could be used as antioxidant, antibiotic as well as new natural skin lightening agents. Also, possible implication of aromatic compounds in anti-tyrosinase activity is discussed.
对六种在北非广泛分布且常用于传统医学的药用盐生植物进行了药理特性筛选，以寻找用于化妆品或营养保健品应用的新的有前景的天然成分来源。因此，对[植物名称1]、[植物名称2]、[植物名称3]、[植物名称4]、[植物名称5]和[植物名称6]进行了抗氧化（DPPH清除、超氧阴离子清除、β-胡萝卜素漂白抑制和铁还原试验）、抗菌（微量稀释法，针对四种人类病原菌）和抗酪氨酸酶活性检测。此外，通过反相高效液相色谱法测定了它们的芳香成分。[植物名称1]茎提取物表现出最强的抗氧化活性，并有效抑制了[细菌名称1]和[细菌名称2]的生长。[植物名称2]和[植物名称3]对单酚酶有轻微抑制作用，而[植物名称4]是二酚酶活性最有效的抑制剂。此外，[植物名称5]表现出最高的芳香成分含量（3.4%干重），主要化合物为多巴胺。这些观察结果表明，[植物名称1]的茎提取物以及程度稍低的[植物名称2]的茎提取物可作为抗氧化剂、抗生素以及新的天然皮肤美白剂。此外，还讨论了芳香化合物在抗酪氨酸酶活性中的可能作用。
