使用18兆电子伏特医用正电子发射断层扫描回旋加速器测量Sc和Sc的产生截面。
Measurement of Sc and Sc production cross-section with an 18MeV medical PET cyclotron.
作者信息
Carzaniga Tommaso Stefano, Auger Martin, Braccini Saverio, Bunka Maruta, Ereditato Antonio, Nesteruk Konrad Pawel, Scampoli Paola, Türler Andreas, van der Meulen Nicholas
机构信息
Albert Einstein Center for Fundamental Physics (AEC), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland; Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland.
Albert Einstein Center for Fundamental Physics (AEC), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland; Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland.
出版信息
Appl Radiat Isot. 2017 Nov;129:96-102. doi: 10.1016/j.apradiso.2017.08.013. Epub 2017 Aug 10.
Sc and Sc are positron emitter radionuclides that, in conjunction with the β emitter Sc, represent one of the most promising possibilities for theranostics in nuclear medicine. Their availability in suitable quantity and quality for medical applications is an open issue and their production with medical cyclotrons represents a scientific and technological challenge. For this purpose, an accurate knowledge of the production cross sections is mandatory. In this paper, we report on the cross section measurement of the reactions Ca(p,n)Sc, Ca(p,2n) Sc, Ti(p,α)Sc, and Ca(p,n)Sc at the Bern University Hospital cyclotron. A study of the production yield and purity performed by using commercially available enriched target materials is also presented.
钪-44和钪-47是正电子发射体放射性核素，与β发射体钪-46一起，是核医学中治疗诊断最有前景的可能性之一。它们以适合医学应用的数量和质量获取是一个悬而未决的问题，并且用医用回旋加速器生产它们是一项科学技术挑战。为此，必须准确了解生产截面。在本文中，我们报告了在伯尔尼大学医院回旋加速器上对反应Ca(p,n)Sc、Ca(p,2n)Sc、Ti(p,α)Sc和Ca(p,n)Sc的截面测量。还介绍了使用市售富集靶材料进行的产率和纯度研究。
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