Lee Tien-Ching, Ho Pei-Shan, Lin Hui-Tzu, Ho Mei-Ling, Huang Hsuan-Ti, Chang Je-Ken
1Orthopaedic Research Center, College of Medicine, Kaohsiung Medical University Hospital.
2Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University Hospital.
Aging Dis. 2017 Jul 21;8(4):402-409. doi: 10.14336/AD.2016.1228. eCollection 2017 Jul.
Early readmission following hip fracture (HFx) is associated with high morbidity and mortality. We conducted a survival analysis of patients with readmission within 1 year after HFx to elucidate the trend and predictors for readmission. We used Taiwan National Health Insurance Database to recruit HFx patients who underwent operations between 2000 and 2009. Patients < 60 years; with pathological fractures; involved in major traffic accidents; with previous pelvis, femur, and hip operations; or who died during the index admission were excluded. We used the Chi-square test, logistic regression, Kaplan-Meier method, and Cox proportional hazards model to analyze variables, including age, gender, hospital stay duration, index admission time, and comorbidity on readmission. 5,442 subjects (61.2% female) met the criteria with mean age of 78.8 years. Approximately 15% and 43% HFx patients were readmitted within 30 days (early) and between 30 days and 1 year (late) after discharge, respectively. Highest readmission incidence was observed within the first 30 days. Most common causes of readmission in early and late groups were respiratory system diseases and injuries, respectively. Cox model showed male, old age, hospital stay > 9 days, Charlson Comorbidity Index ≥ 1, index admission during 2000-2003, and internal fixation of HFx were independent predictors of readmission. One-year mortality of the early and the late readmission groups was 44.9% and 32.3%, much higher than overall mortality which was 16.8%. Predictive factors for readmission within 1 year included male, old age, comorbidities, and longer hospital stay. One-year mortality in readmitted patients was significantly higher. HFx patients with these factors need careful follow-up, especially within 30 days after discharge.
髋部骨折(HFx)后早期再入院与高发病率和死亡率相关。我们对HFx后1年内再入院的患者进行了生存分析,以阐明再入院的趋势和预测因素。我们使用台湾国民健康保险数据库招募了2000年至2009年间接受手术的HFx患者。排除年龄<60岁、病理性骨折、涉及重大交通事故、既往有骨盆、股骨和髋部手术史或在首次入院期间死亡的患者。我们使用卡方检验、逻辑回归、Kaplan-Meier方法和Cox比例风险模型分析变量,包括年龄、性别、住院时间、首次入院时间和再入院时的合并症。5442名受试者(61.2%为女性)符合标准,平均年龄为78.8岁。分别约15%和43%的HFx患者在出院后30天内(早期)和30天至1年之间(晚期)再入院。再入院发生率在最初30天内最高。早期和晚期组再入院的最常见原因分别是呼吸系统疾病和损伤。Cox模型显示,男性、老年、住院时间>9天、Charlson合并症指数≥1、2000 - 2003年期间首次入院以及HFx的内固定是再入院的独立预测因素。早期和晚期再入院组的1年死亡率分别为44.9%和32.3%,远高于总体死亡率16.8%。1年内再入院的预测因素包括男性、老年、合并症和更长的住院时间。再入院患者的1年死亡率显著更高。具有这些因素的HFx患者需要仔细随访,尤其是在出院后30天内。