使用自动血液分析仪评估小鼠红细胞和血小板计数。
Evaluation of mouse red blood cell and platelet counting with an automated hematology analyzer.
作者信息
Fukuda Teruko, Asou Eri, Nogi Kimiko, Goto Kazuo
机构信息
Department of Clinical Laboratory Medicine, Teikyo University, 2-1-11 Kaga Itabashi, Tokyo 173-8605, Japan.
Teikyo University Hospital, 2-1-11 Kaga, Itabashi, Tokyo 173-0005, Japan.
出版信息
J Vet Med Sci. 2017 Oct 7;79(10):1707-1711. doi: 10.1292/jvms.17-0387. Epub 2017 Aug 27.
An evaluation of mouse red blood cell (RBC) and platelet (PLT) counting with an automated hematology analyzer was performed with three strains of mice, C57BL/6 (B6), BALB/c (BALB) and DBA/2 (D2). There were no significant differences in RBC and PLT counts between manual and automated optical methods in any of the samples, except for D2 mice. For D2, RBC counts obtained using the manual method were significantly lower than those obtained using the automated optical method (P<0.05), and PLT counts obtained using the manual method were higher than those obtained using the automated optical method (P<0.05). An automated hematology analyzer can be used for RBC and PLT counting; however, an appropriate method should be selected when D2 mice samples are used.
使用自动血液分析仪对三种品系的小鼠，即C57BL/6（B6）、BALB/c（BALB）和DBA/2（D2）的红细胞（RBC）和血小板（PLT）计数进行了评估。除D2小鼠外，在任何样本中，手动和自动光学方法之间的RBC和PLT计数均无显著差异。对于D2小鼠，使用手动方法获得的RBC计数显著低于使用自动光学方法获得的计数（P<0.05），且使用手动方法获得的PLT计数高于使用自动光学方法获得的计数（P<0.05）。自动血液分析仪可用于RBC和PLT计数；然而，当使用D2小鼠样本时，应选择合适的方法。
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