Burg J R, Hardin B D
Teratog Carcinog Mutagen. 1987;7(1):49-54. doi: 10.1002/tcm.1770070107.
The statistical analyses of the data related to the teratogenic testing of 60 compounds utilizing the Chernoff/Kavlock test are the basis of this paper. The hypotheses chosen to be tested and the statistical tests utilized to test those hypotheses are discussed. The topics explored are the use of comparisonwise error rate versus experimentwise error rate, the use of nonparametric tests versus more "conventional" parametric tests and the use of "historical data" in assessing and interpreting group difference.
本文以利用切尔诺夫/卡夫洛克试验对60种化合物进行致畸性测试所获得的数据统计分析为基础。文中讨论了所选择要检验的假设以及用于检验这些假设的统计检验方法。探讨的主题包括比较误差率与实验误差率的使用、非参数检验与更“传统”的参数检验的使用，以及在评估和解释组间差异时“历史数据”的使用。
