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外周来源的血浆γ-氨基丁酸(GABA)是吗?

Is plasma GABA of peripheral origin?

作者信息

Petty F, Kramer G, Feldman M

出版信息

Biol Psychiatry. 1987 Jun;22(6):725-32. doi: 10.1016/0006-3223(87)90204-6.

DOI:10.1016/0006-3223(87)90204-6
PMID:2885038
Abstract

Plasma levels of gamma-aminobutyric acid (GABA) appear to be altered in affective disorders and alcoholism. Plasma levels of GABA were not affected by menstrual cycle, exercise, gender, gut flora, nor by cholinergic stimulation by bethanechol. An obvious peripheral source for plasma GABA could not be demonstrated.

摘要

γ-氨基丁酸(GABA)的血浆水平在情感障碍和酒精中毒中似乎会发生改变。GABA的血浆水平不受月经周期、运动、性别、肠道菌群的影响,也不受氨甲酰甲胆碱的胆碱能刺激的影响。无法证明血浆GABA有明显的外周来源。

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