Dai Z, Lang W, Yang H, Tian J, Sun W, Pekbay B, Lin Y, Wang M, Cui B, Yang S, Li H, Luo L, Guo H, Zhang L
Key Laboratory of Cancer Prevention and Therapy, Department of Endoscopy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Tianjin Medical University, Tianjin, China.
Dis Esophagus. 2017 Oct 1;30(10):1-7. doi: 10.1093/dote/dox046.
The aim of this study is to evaluate the reliability, validity, and acceptability of the Chinese version of the EORTC QLQ-OES18 in patients with esophageal cancer. The questionnaire was translated according to the guideline of the EORTC. One hundred and forty-nine patients with esophageal cancer from Tianjin Medical University Cancer Institute and Hospital completed the Karnofsky performance scale (KPS) and the simplified Chinese EORTC QLQ-C30/OES18 scales during July 2013 to January 2014. The results were statistically analyzed by Cronbach's α coefficient, Spearman correlation test with multiple strengthen analysis, and Wilcoxon Rank Sum test. The internal consistency (Cronbach's α coefficient) of all four scales (dysphagia, eating, reflux, and pain) was 0.689-0.822, which were satisfactory or near satisfactory. The absolute values of correlation of each scale between EORTC QLQ-OES18 and EORTC QLQ-C30 were 0.002-0.750 while there was no significant difference between groups divided by KPS scores. We confirmed the Chinese version of EORTC QLQ-OES18 appears to be a reliable, valid, and acceptable instrument for measuring the health-related quality of life of patients with esophageal cancer in mainland China.
本研究旨在评估欧洲癌症研究与治疗组织（EORTC）QLQ-OES18中文版在食管癌患者中的信度、效度和可接受性。该问卷是根据EORTC的指南进行翻译的。2013年7月至2014年1月期间，天津医科大学肿瘤医院的149例食管癌患者完成了卡氏功能状态量表（KPS）以及EORTC QLQ-C30/OES18中文版简化量表。结果采用Cronbach's α系数、Spearman相关检验及多重强化分析、Wilcoxon秩和检验进行统计学分析。所有四个量表（吞咽困难、进食、反流和疼痛）的内部一致性（Cronbach's α系数）为0.689 - 0.822，结果令人满意或接近满意。EORTC QLQ-OES18与EORTC QLQ-C30各量表之间的相关绝对值为0.002 - 0.750，而按KPS评分分组的各小组之间无显著差异。我们证实，EORTC QLQ-OES18中文版似乎是一种可靠、有效且可接受的工具，用于衡量中国大陆食管癌患者与健康相关的生活质量。
