Departments of Pediatrics, Pediatric Cardiology & Public Health Research, Amrita Vishwa Vidyapeetham University, Kochi, India.
Department of Pediatric Cardiology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham University, Kochi, India.
Indian J Med Res. 2017 Apr;145(4):521-529. doi: 10.4103/ijmr.IJMR_447_16.
BACKGROUND & OBJECTIVES: There are limited data on health-related quality of life (HRQOL) related to Indian children. The objective of this study was to construct a generic HRQOL reference for children aged 2-18 yr from a community setting.
The study was a community-based cross-sectional survey. A total of 719 children/adolescents in the age group of 2-18 yr were enrolled using stratified random cluster sampling. A total of 40 clusters (cluster size 18) were selected for the study. The data contained child self-report and parent proxy report from healthy children and their parents/caretakers. The Pediatric Quality of Life Inventory 4.0 (PedsQL4.0) Generic Core Scale was used to collect HRQOL data. Questionnaires were self-administered for parents and children aged 8-18 yr. In the age group of five to seven years, parents assisted the children in filling questionnaires.
The mean HRQOL total scores from child self-report and parent proxy report were 87.50±11.10 and 90.10±9.50 respectively, for children aged 2-18 yr. Social functioning had the highest scores and emotional functioning had the lowest scores for the entire sample and subgroups. The mean values for HRQOL in the current study were significantly different from the reference study for both child (87.39 vs. 83.91, P<0.001) and parent proxy reports (90.03 vs. 82.29, P<0.001) when compared between children aged 2-16 yr.
INTERPRETATION & CONCLUSIONS: The study provided reference values for HRQOL in healthy children and adolescents from Kerala, India, that appeared to be different from existing international reference. Similar studies need to be done in different parts of India to generate a country-specific HRQOL reference for Indian children.
有关印度儿童的健康相关生活质量（HRQOL）数据有限。本研究的目的是构建一个来自社区环境的 2-18 岁儿童通用 HRQOL 参考值。
这是一项基于社区的横断面调查。共纳入 719 名年龄在 2-18 岁的儿童/青少年，采用分层随机聚类抽样。共选择了 40 个（集群大小为 18）集群进行研究。数据包含来自健康儿童及其父母/照顾者的儿童自我报告和父母代理报告。使用儿科生活质量问卷 4.0（PedsQL4.0）通用核心量表收集 HRQOL 数据。问卷由 8-18 岁的父母和儿童自行填写。在五岁至七岁年龄组，父母协助孩子填写问卷。
2-18 岁儿童的儿童自我报告和父母代理报告的 HRQOL 总分平均值分别为 87.50±11.10 和 90.10±9.50。整个样本和亚组的社会功能得分最高，情感功能得分最低。与参考研究相比，当前研究中 HRQOL 的平均值在儿童（87.39 与 83.91，P<0.001）和父母代理报告（90.03 与 82.29，P<0.001）方面均存在显著差异。当比较 2-16 岁儿童时，这两个值均存在显著差异。
该研究提供了来自印度喀拉拉邦健康儿童和青少年 HRQOL 的参考值，这些参考值似乎与现有的国际参考值不同。需要在印度不同地区进行类似的研究，以生成印度儿童特定的 HRQOL 参考值。
