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心理困扰与生活质量:孟加拉国一个农村地区前瞻性队列研究的基本原理与方案

Psychological distress and quality of life: rationale and protocol of a prospective cohort study in a rural district in Bangaladesh.

作者信息

Uddin Mohammed Nazim, Bhar Sunil, Al Mahmud Abdullah, Islam Fakir M Amirul

机构信息

Department of Statistics, Data Science and Epidemiology, Swinburne University of Technology, Hawthorn, Victoria, Australia.

Department of Psychological Sciences, Swinburne University of Technology, Hawthorn, Victoria, Australia.

出版信息

BMJ Open. 2017 Sep 1;7(9):e016745. doi: 10.1136/bmjopen-2017-016745.

DOI:10.1136/bmjopen-2017-016745
PMID:28864700
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5588978/
Abstract

INTRODUCTION

A significant proportion of the global burden of disease has been attributed to mental and behavioural disorders. People with mental disorders (MDs) have lower levels of health-related quality of life than those without MDs. Several studies have shown that in low-resource countries, a range of social determinants including poor health literacy is critical in the epidemiological transition of disease outcome. There is a lack of evidence of MDs literacy, the prevalence and risk factors of common mental health conditions, or any validated instruments to measure psychological distress or evaluate the quality of life in rural areas of Bangladesh.

AIMS

The aims of this study are: (1) report the awareness, knowledge, attitudes and practice (KAP) of MDs; (2) estimate the prevalence of and risk factors for psychological distress; (3) measure association of psychological distress and other socio-demographic factors with quality of life and (4) test the feasibility to use Kessler 10-item (K10) and WHO Quality Of Life-BREF (WHOQOL-BREF) questionnaires in rural Bangladesh for measuring psychological distress and quality of life.

METHODS AND ANALYSIS

A sample of 1500 adults aged 18-59 years and 1200 older adults aged 60-90 years will be interviewed from a multistage cluster random sample. Each participant will go through a face-to-face interview to assess their awareness and KAP of MDs. Information about the participant's sociodemographic and socioeconomic status will be collected along with the psychological distress (K10) and quality of life (WHOQOL-BREF) questionnaires. Internal consistency, validity, reliability and item discrimination of K10 and WHOQOL-BREF instruments will be determined by using Rasch analysis and regression techniques.

ETHICS AND DISSEMINATION

Human Ethics Approval was received from the Swinburne University of Technology Human Ethics Committee. Results of this research will be disseminated via scientific forums including peer-reviewed publications and presentations at national and international conferences.

摘要

引言

全球疾病负担的很大一部分归因于精神和行为障碍。患有精神障碍的人群与健康相关的生活质量水平低于未患精神障碍的人群。多项研究表明,在资源匮乏的国家,包括健康素养低下在内的一系列社会决定因素在疾病结局的流行病学转变中至关重要。目前缺乏关于精神障碍素养、常见心理健康状况的患病率和风险因素的证据,也没有任何经过验证的工具来测量心理困扰或评估孟加拉国农村地区的生活质量。

目的

本研究的目的是:(1)报告对精神障碍的知晓度、知识、态度和实践(KAP);(2)估计心理困扰的患病率及其风险因素;(3)测量心理困扰及其他社会人口学因素与生活质量之间的关联;(4)测试在孟加拉国农村地区使用凯斯勒10项量表(K10)和世界卫生组织生活质量简表(WHOQOL-BREF)问卷来测量心理困扰和生活质量的可行性。

方法与分析

将从多阶段整群随机样本中选取1500名年龄在18至59岁之间的成年人以及1200名年龄在60至90岁之间的老年人作为样本进行访谈。每位参与者都将接受面对面访谈,以评估他们对精神障碍的知晓度和KAP。将收集参与者的社会人口学和社会经济状况信息,同时发放心理困扰(K10)和生活质量(WHOQOL-BREF)问卷。将使用拉施分析和回归技术来确定K10和WHOQOL-BREF工具的内部一致性、效度、信度和项目区分度。

伦理与传播

已获得斯威本科技大学人类伦理委员会的人类伦理批准。本研究结果将通过科学论坛进行传播,包括同行评审出版物以及在国内和国际会议上的报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/426a/5588978/caaf8eddb261/bmjopen-2017-016745f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/426a/5588978/caaf8eddb261/bmjopen-2017-016745f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/426a/5588978/caaf8eddb261/bmjopen-2017-016745f01.jpg

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