Li M, Liu D R, Qu C Y, Zhang P Y, Qian Q D, Zhang C D, Jia Q Z, Wang H X, Eastman C J, Boyages S C
Lancet. 1987 Aug 1;2(8553):257-9.
Thyroid status was examined in children from two villages in central China where the iodine concentrations in drinking water were 462.5 and 54 micrograms/l. Goitres were present in 65% (n = 120) and 15.4% (n = 51), respectively. All children in both groups were clinically euthyroid and neurologically normal. Growth measurements and intellectual performance were similar in the two groups. Children from the high-iodine village had a lower mean serum triiodothyronine and higher serum free thyroxine and serum thyroid-stimulating hormone concentrations than the children from the control village. 2 cases of overt hypothyroidism were detected in the high-iodine village.
对中国中部两个村庄的儿童进行了甲状腺状况检查，这两个村庄饮用水中的碘浓度分别为462.5微克/升和54微克/升。甲状腺肿的发生率分别为65%（n = 120）和15.4%（n = 51）。两组所有儿童的临床甲状腺功能均正常，神经功能也正常。两组儿童的生长指标和智力表现相似。高碘村儿童的血清三碘甲状腺原氨酸平均水平较低，血清游离甲状腺素和血清促甲状腺激素浓度高于对照村儿童。在高碘村检测到2例显性甲状腺功能减退病例。
