Tao Jing, Liu Jiao, Liu Weilin, Huang Jia, Xue Xiehua, Chen Xiangli, Wu Jinsong, Zheng Guohua, Chen Bai, Li Ming, Sun Sharon, Jorgenson Kristen, Lang Courtney, Hu Kun, Chen Shanjia, Chen Lidian, Kong Jian
College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Fujian Key Laboratory of Rehabilitation Technology, Fuzhou, China.
J Alzheimers Dis. 2017;60(2):389-400. doi: 10.3233/JAD-170477.
The aim of this study is to investigate and compare how 12-weeks of Tai Chi Chuan and Baduanjin exercise can modulate brain structure and memory function in older adults. Magnetic resonance imaging and memory function measurements (Wechsler Memory Scale-Chinese revised, WMS-CR) were applied at both the beginning and end of the study. Results showed that both Tai Chi Chuan and Baduanjin could significantly increase grey matter volume (GMV) in the insula, medial temporal lobe, and putamen after 12-weeks of exercise. No significant differences were observed in GMV between the Tai Chi Chuan and Baduanjin groups. We also found that compared to healthy controls, Tai Chi Chuan and Baduanjin significantly improved visual reproduction subscores on the WMS-CR. Baduanjin also improved mental control, recognition, touch, and comprehension memory subscores of the WMS-CR compared to the control group. Memory quotient and visual reproduction subscores were both associated with GMV increases in the putamen and hippocampus. Our results demonstrate the potential of Tai Chi Chuan and Baduanjin exercise for the prevention of memory deficits in older adults.
本研究旨在调查并比较为期12周的太极拳和八段锦锻炼如何调节老年人的脑结构和记忆功能。在研究开始和结束时均进行了磁共振成像和记忆功能测量（中文版韦氏记忆量表，WMS-CR）。结果显示，经过12周的锻炼，太极拳和八段锦均可显著增加脑岛、内侧颞叶和壳核的灰质体积（GMV）。太极拳组和八段锦组之间的GMV未观察到显著差异。我们还发现，与健康对照组相比，太极拳和八段锦显著提高了WMS-CR上的视觉再现子分数。与对照组相比，八段锦还改善了WMS-CR的心理控制、识别、触觉和理解记忆子分数。记忆商数和视觉再现子分数均与壳核和海马体的GMV增加有关。我们的结果证明了太极拳和八段锦锻炼在预防老年人记忆缺陷方面的潜力。
