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前庭神经鞘瘤的保守治疗:法语版的生长情况及宾夕法尼亚听神经瘤生活质量量表

Conservative treatment of vestibular schwannoma: growth and Penn Acoustic Neuroma Quality of Life scale in French language.

作者信息

Oddon P A, Montava M, Salburgo F, Collin M, Vercasson C, Lavieille J P

机构信息

APHM, Hôpital de la Conception, Service d'Oto-rhino-laryngologie et de Chirurgie cervico-faciale, Marseille, France.

Aix Marseille Université, IFSSTAR, LBA, UMR-T 24, Marseille, France.

出版信息

Acta Otorhinolaryngol Ital. 2017 Aug;37(4):320-327. doi: 10.14639/0392-100X-1094.

Abstract

The aim of this study was to determine the natural history of growth and quality of life (QoL) outcomes for vestibular schwannoma (VS) managed conservatively, and to validate the disease-specific Penn Acoustic Neuroma Quality-of-Life (PANQOL) scale in French language. We retrospectively studied 26 patients with VS managed conservatively. Patient characteristics and radiological findings were collected. Two scales were used to measure QoL: the Short Form-36 Health Survey (SF-36) and the PANQOL scale translated into French. Internal consistency and scores were compared with previous studies. The mean follow-up was 25 months (range 6-72). We observed tumour growth in 14 patients (53.8%), no growth in 12 patients (46.2%) and no case of tumour shrinkage. The mean tumour growth was 2.22 mm/year. No predictive factor of growth was found. Patients with vertigo or dizziness experienced a poorer QoL according to the SF-36 (Social Functioning and Emotional Role Limitation dimensions) and to the PANQOL scale (Balance and Energy dimensions). Our results were comparable with the literature using the SF-36. With the PANQOL scale, our scores were not statistically different with those from Dutch and North American studies except in the field of hearing (p = 0.019). Quality of life becomes essential in the management of VS. According to these results, we support a non-conservative strategy associated with vestibular rehabilitation for patients with dizziness or vertigo. The PANQOL is a validated specific scale for VS, which can be useful in French.

摘要

本研究的目的是确定保守治疗的前庭神经鞘瘤(VS)的生长自然史和生活质量(QoL)结果,并验证法语版的疾病特异性宾夕法尼亚听神经瘤生活质量(PANQOL)量表。我们回顾性研究了26例接受保守治疗的VS患者。收集了患者特征和影像学检查结果。使用两个量表来测量生活质量:简明健康调查量表(SF-36)和翻译成法语的PANQOL量表。将内部一致性和得分与先前的研究进行比较。平均随访时间为25个月(范围6-72个月)。我们观察到14例患者(53.8%)肿瘤生长,12例患者(46.2%)无生长,无肿瘤缩小病例。平均肿瘤生长速度为2.22毫米/年。未发现生长的预测因素。根据SF-36(社会功能和情感角色限制维度)和PANQOL量表(平衡和能量维度),有眩晕或头晕的患者生活质量较差。我们使用SF-36的结果与文献报道相当。使用PANQOL量表时,除听力领域外(p = 0.019),我们的得分与荷兰和北美研究的得分无统计学差异。生活质量在VS的治疗中变得至关重要。根据这些结果,我们支持对有头晕或眩晕的患者采取与前庭康复相关的非保守策略。PANQOL是一种经过验证的VS特异性量表,在法语中可能有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b84f/5584105/2c338325ec28/0392-100X-37-320-g001.jpg

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