Tchoukoua Abdou, Hasegawa Ryosuke, Hendracipta Kurniawan Andreas, Sato Satoru, Koseki Takuya, Shiono Yoshihito
Department of Organic Chemistry, Faculty of Science, University of Yaounde I, Yaounde, Cameroon.
Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Yamagata, Japan.
Magn Reson Chem. 2018 Jan;56(1):32-36. doi: 10.1002/mrc.4662. Epub 2017 Sep 21.
Three new fusarielins, 3-epi-fusarielin H (1), 3-O-methyl-fusarielin H (2), and 3-O-methyl-epi-fusarielin H (3), were isolated from the fungus Fusarium sp. together with the known analogues, fusarielins F (4) and G (5). The structures of these compounds were elucidated by analysis of their ESI-HRTOFMS, 1D and 2D NMR spectroscopic data. The new compounds exhibited weak antibacterial effect against Staphylococcus aureus.
从镰刀菌属真菌中分离出三种新的镰孢菌素，即3-表镰孢菌素H（1）、3-O-甲基镰孢菌素H（2）和3-O-甲基-表镰孢菌素H（3），以及已知类似物镰孢菌素F（4）和G（5）。通过对它们的电喷雾高分辨飞行时间质谱（ESI-HRTOFMS）、一维和二维核磁共振光谱数据的分析，阐明了这些化合物的结构。这些新化合物对金黄色葡萄球菌表现出微弱的抗菌作用。
