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Immun Inflamm Dis. 2025 Mar;13(3):e70183. doi: 10.1002/iid3.70183.

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Clinical and Imaging Signs of Spondyloarthritis in First-Degree Relatives of HLA-B27-Positive Ankylosing Spondylitis Patients: The Pre-Spondyloarthritis (Pre-SpA) Cohort Study.HLA-B27 阳性强直性脊柱炎患者一级亲属的脊柱关节炎临床和影像学表现:前脊柱关节炎(Pre-SpA)队列研究。
Arthritis Rheumatol. 2016 Oct;68(10):2444-55. doi: 10.1002/art.39766.
2
ZAP-70 genotype disrupts the relationship between microbiota and host, leading to spondyloarthritis and ileitis in SKG mice.ZAP-70 基因型破坏了微生物群和宿主之间的关系,导致 SKG 小鼠发生脊椎关节炎和回肠炎。
Arthritis Rheumatol. 2014 Oct;66(10):2780-92. doi: 10.1002/art.38773.
3
Does spinal MRI add incremental diagnostic value to MRI of the sacroiliac joints alone in patients with non-radiographic axial spondyloarthritis?对于非放射性轴性脊柱关节炎患者,脊柱 MRI 是否比单独的骶髂关节 MRI 具有更多的附加诊断价值?
Ann Rheum Dis. 2015 Jun;74(6):985-92. doi: 10.1136/annrheumdis-2013-203887. Epub 2014 Jan 22.
4
Elevated serum anti-flagellin antibodies implicate subclinical bowel inflammation in ankylosing spondylitis: an observational study.血清抗鞭毛蛋白抗体升高提示强直性脊柱炎存在亚临床肠道炎症:一项观察性研究。
Arthritis Res Ther. 2013 Oct 26;15(5):R166. doi: 10.1186/ar4350.
5
Development, sensibility, and reliability of the Toronto Axial Spondyloarthritis Questionnaire in inflammatory bowel disease.炎症性肠病患者多伦多轴向脊柱关节炎问卷的开发、敏感性和可靠性。
J Rheumatol. 2013 Oct;40(10):1726-35. doi: 10.3899/jrheum.130048. Epub 2013 Sep 1.
6
Markers of intestinal inflammation in patients with ankylosing spondylitis: a pilot study.强直性脊柱炎患者肠道炎症标志物:一项初步研究。
Arthritis Res Ther. 2012 Nov 29;14(6):R261. doi: 10.1186/ar4106.
7
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.宿主-微生物相互作用塑造了炎症性肠病的遗传结构。
Nature. 2012 Nov 1;491(7422):119-24. doi: 10.1038/nature11582.
8
Pathophysiology and role of the gastrointestinal system in spondyloarthritides.胃肠道系统在脊椎关节炎中的病理生理学和作用。
Rheum Dis Clin North Am. 2012 Aug;38(3):569-82. doi: 10.1016/j.rdc.2012.08.012. Epub 2012 Sep 13.
9
Serological markers predict inflammatory bowel disease years before the diagnosis.血清标志物可在炎症性肠病诊断前数年预测疾病。
Gut. 2013 May;62(5):683-8. doi: 10.1136/gutjnl-2012-302717. Epub 2012 Jul 26.
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Calprotectin in ankylosing spondylitis--frequently elevated in feces, but normal in serum.强直性脊柱炎中的钙卫蛋白——在粪便中常升高,但在血清中正常。
Scand J Gastroenterol. 2012 Apr;47(4):435-44. doi: 10.3109/00365521.2011.648953. Epub 2012 Jan 10.

Relationship between the gut and the spine: a pilot study of first-degree relatives of patients with ankylosing spondylitis.

作者信息

Kehl Amy S, Learch Thomas J, Li Dalin, McGovern Dermot P B, Weisman Michael H

机构信息

Department of Rheumatology, University of California Los Angeles, Los Angeles, California, USA.

Department of Radiology, Cedars-Sinai Medical Center, Los Angeles, California, USA.

出版信息

RMD Open. 2017 Aug 16;3(2):e000437. doi: 10.1136/rmdopen-2017-000437. eCollection 2017.

DOI:10.1136/rmdopen-2017-000437
PMID:28879050
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5574426/
Abstract
摘要