MOE Key Laboratory of Macromolecular Synthesis and Functionalization, and ‡Department of Polymer Science and Engineering, Key Laboratory of Adsorption and Separation Materials & Technologies of Zhejiang Province, Zhejiang University , Hangzhou 310027, China.
ACS Appl Mater Interfaces. 2017 Oct 4;9(39):34356-34366. doi: 10.1021/acsami.7b11092. Epub 2017 Sep 19.
Surface modification has been well recognized as a promising strategy to design and exploit diversified functional materials. However, conventional modification strategies usually suffer from complicated manufacture procedures and lack of universality. Herein, a facile, robust, and versatile approach is proposed to achieve the surface functionalization using dopamine and acrylate monomers via a one-step polymerization and codeposition process. The gel permeation chromatography, proton nuclear magnetic resonance, liquid chromatography-mass spectrometry, and UV-visible spectra results indicate that dopamine possesses the capability of triggering the polymerization of acrylate monomers into high-molecular-weight products, and the inherent adhesive ability of polydopamine can assist the polymerized products to deposit on various substrates. Besides, protein-resistant, antibacterial, and cell adhesion-resistant surfaces can be easily fabricated via the finely designed integration of corresponding acrylate monomers into the codeposition systems. This approach of in situ polymerization and codeposition significantly simplifies the fabrication process and provides more manifold choices for surface modification, which will open a new door for broadening the applications of polydopamine-based coatings.
表面改性已被广泛认为是设计和开发多样化功能材料的一种很有前途的策略。然而，传统的改性策略通常存在制造工艺复杂和缺乏通用性的问题。在此，提出了一种简便、鲁棒、通用的方法，使用多巴胺和丙烯酸酯单体通过一步聚合和共沉积过程来实现表面功能化。凝胶渗透色谱、质子核磁共振、液相色谱-质谱和紫外可见光谱结果表明，多巴胺具有引发丙烯酸酯单体聚合生成高分子量产物的能力，而聚多巴胺的固有粘附能力可以帮助聚合产物沉积在各种基底上。此外，通过将相应的丙烯酸酯单体精细地设计集成到共沉积系统中，可以很容易地制备出抗蛋白、抗菌和抗细胞黏附的表面。这种原位聚合和共沉积的方法显著简化了制造过程，并为表面改性提供了更多的选择，为基于聚多巴胺的涂层的应用开辟了新的途径。
