Ozsoy Arzu, Barca Nurdan, Dolek Betul Akdal, Aktaş Hafize, Elverici Eda, Araz Levent, Ozkaraoğlu Ozlen
Clinic of Radiology, Ankara Numune Hospital, Ankara, Turkey.
Eur J Breast Health. 2017 Apr 4;13(3):145-149. doi: 10.5152/tjbh.2017.3180. eCollection 2017 Jul.
To determine the relationship between breast cancer and known risk factors in patients who had mammography (MG) for breast cancer screening or ultrasonography and/or MG for diagnostic purposes.
In the period of January-December, 2011, a questionnaire composed of 17 questions was applied to 2862 female patients and MG and/or US examination was performed afterwards. Chi-square and Kruskal-Wallis tests were used for statistical analysis.
The mean age was 51.05±8.98, age at menarche was 13.0±1.6 and age at menopause was 47±5.2. The first pregnancy was at 20±4.6. Out of 2862 cases, 242 had breast cancer diagnosis and 32 were newly diagnosed. There was no correlation between menarche age, age at menopause or first pregnancy and breast cancer. There was no relationship between breast cancer risk and hormone replacement therapy or oral contraceptive use. In patients with the diagnosis of breast cancer (242 cases), 61 had (25%) a positive family history. There was a significant correlation between the presence of a positive family history and having breast cancer (p=0.003).
The presence of breast cancer in the family has the strongest relationship among all risk factors. It is important to have regular followup of these patients and to raise the awareness of patients.
确定在因乳腺癌筛查进行乳房X线摄影（MG）或因诊断目的进行超声检查和/或MG的患者中，乳腺癌与已知风险因素之间的关系。
在2011年1月至12月期间，对2862名女性患者应用了一份由17个问题组成的问卷，随后进行了MG和/或超声检查。采用卡方检验和克鲁斯卡尔-沃利斯检验进行统计分析。
平均年龄为51.05±8.98岁，初潮年龄为13.0±1.6岁，绝经年龄为47±5.2岁。首次怀孕年龄为20±4.6岁。在2862例病例中，242例被诊断为乳腺癌，32例为新诊断病例。初潮年龄、绝经年龄或首次怀孕与乳腺癌之间无相关性。乳腺癌风险与激素替代疗法或口服避孕药的使用之间无关系。在诊断为乳腺癌的患者（242例）中，61例（25%）有阳性家族史。阳性家族史的存在与患乳腺癌之间存在显著相关性（p = 0.003）。
在所有风险因素中，家族中有乳腺癌患者的相关性最强。对这些患者进行定期随访并提高患者的意识很重要。
