Özdemir Abdurrahman Avar, Ercan Gündemir Yasemin, Küçük Mustafa, Yıldıran Sarıcı Deniz, Elgörmüş Yusuf, Çağ Yakup, Bilek Günal
Biruni University, Medicine Hospital, Clinic of Pediatrics, İstanbul, Turkey.
Biruni University, Medicine Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey.
J Clin Res Pediatr Endocrinol. 2018 Mar 1;10(1):44-50. doi: 10.4274/jcrpe.4706. Epub 2017 Sep 13.
Vitamin D deficiency is a serious health problem despite a general improvement in socio-economic status in Turkey. The aim of this study was to evaluate maternal vitamin D status and its effect on neonatal vitamin D concentrations after a support programme for pregnant women was introduced. A second aim was to identify risk factors for vitamin D deficiency in a district of İstanbul.
A total of 97 pregnant women and 90 infants were included in this study, conducted between January and October 2016. The demographic data, risk factors and daily vitamin intake were recorded. Serum levels of vitamin D, calcium, phosphorus and alkaline phosphatase in all subjects were measured. The mothers and newborns were divided into groups based on their vitamin D levels. The relationship between vitamin D levels and risk factors was analyzed.
Mean ± standard deviation vitamin D levels for the women and their infants were found to be 14.82±11.45 and 13.16±7.16 ng/mL, respectively. The number of mothers and infants was significantly higher in the deficient group, and their mean vitamin D levels significantly lower (9.02±1.34 and 8.80±1.06 ng/mL, respectively) (p<0.001, p<0.001). Only 14.4% of pregnant women took 1000-1200 IU/day of vitamin D. When the mother groups were evaluated in terms of risk factors, there were significant differences in daily vitamin intake and clothing style (p<0.001 and p<0.001 respectively).
Vitamin D deficiency in pregnant women and their infants is still a serious health problem in Turkey, although a vitamin D support programme during pregnancy has been launched by the department of health.
尽管土耳其社会经济状况普遍改善，但维生素D缺乏仍是一个严重的健康问题。本研究的目的是在引入针对孕妇的支持项目后，评估母亲的维生素D状况及其对新生儿维生素D浓度的影响。第二个目的是确定伊斯坦布尔一个地区维生素D缺乏的风险因素。
本研究于2016年1月至10月进行，共纳入97名孕妇和90名婴儿。记录人口统计学数据、风险因素和每日维生素摄入量。测量所有受试者血清中的维生素D、钙、磷和碱性磷酸酶水平。根据母亲和新生儿的维生素D水平将他们分组。分析维生素D水平与风险因素之间的关系。
发现女性及其婴儿的维生素D水平平均±标准差分别为14.82±11.45和13.16±7.16 ng/mL。缺乏组的母亲和婴儿数量显著更高，他们的平均维生素D水平显著更低（分别为9.02±1.34和8.80±1.06 ng/mL）（p<0.001，p<0.001）。只有14.4%的孕妇每天摄入1000 - 1200 IU的维生素D。当根据风险因素评估母亲组时，每日维生素摄入量和着装风格存在显著差异（分别为p<0.001和p<0.001）。
尽管卫生部已启动孕期维生素D支持项目，但土耳其孕妇及其婴儿的维生素D缺乏仍然是一个严重的健康问题。
