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抗生素治疗儿童急性中耳炎。

Antibiotic therapy for children with acute otitis media.

出版信息

Can Fam Physician. 2017 Sep;63(9):685-687.

PMID:28904032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5597011/
Abstract

Acute otitis media is one of the most common infections in childhood. Routine prescription of antibiotics has led to adverse events and bacterial resistance to antibiotics. I have heard that "watchful waiting" is a good strategy to reduce this potential problem in children older than 6 months of age. Should I apply this strategy in my clinical practice? Watchful waiting can be applied in selected children with nonsevere acute otitis media by withholding antibiotics and observing the child for clinical improvement. Antibiotics should be promptly provided if the child's infection worsens or fails to improve within 24 to 48 hours. Guidelines and most ongoing studies support these recommendations. Correct choice of regimen, dose, frequency, and length of treatment are all important.

摘要

急性中耳炎是儿童最常见的感染之一。常规开具抗生素处方导致了不良事件和抗生素耐药性。我听说“静观等待”是减少 6 个月以上儿童潜在问题的好策略。我是否应该在我的临床实践中应用这种策略?

在选择非重度急性中耳炎的儿童中,可以通过不使用抗生素并观察儿童的临床改善情况来应用静观等待。如果儿童的感染在 24 至 48 小时内恶化或没有改善,应立即提供抗生素。指南和大多数正在进行的研究都支持这些建议。正确选择治疗方案、剂量、频率和疗程都很重要。

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本文引用的文献

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Pediatric Acute Otitis Media in the Era of Pneumococcal Vaccination.肺炎球菌疫苗时代的小儿急性中耳炎
Otolaryngol Head Neck Surg. 2017 May;156(5):938-945. doi: 10.1177/0194599817699599. Epub 2017 Mar 28.
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Predominant Bacteria Detected from the Middle Ear Fluid of Children Experiencing Otitis Media: A Systematic Review.从患中耳炎儿童中耳液中检测出的主要细菌:一项系统评价
PLoS One. 2016 Mar 8;11(3):e0150949. doi: 10.1371/journal.pone.0150949. eCollection 2016.
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Antibiotics for acute otitis media in children.儿童急性中耳炎的抗生素治疗
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Severe Acute Mastoiditis Admission is Not Related to Delayed Antibiotic Treatment for Antecedent Acute Otitis Media.重度急性乳突炎的入院情况与前期急性中耳炎的抗生素延迟治疗无关。
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