N-杂环卡宾催化 2-硝基半乳糖醛的立体选择性糖基化反应。
N-Heterocyclic Carbene Catalyzed Stereoselective Glycosylation of 2-Nitrogalactals.
机构信息
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University , Xi'an 710127, P. R. China.
出版信息
Org Lett. 2017 Oct 6;19(19):5272-5275. doi: 10.1021/acs.orglett.7b02543. Epub 2017 Sep 14.
PMID:28906121
Abstract
An efficient N-heterocyclic carbene catalyzed glycosylation of 2-nitrogalactals with alcohols and phenol has been developed for the first time. A wide variety of 1,2-cis-2-nitroglycosides can be obtained with good to excellent yields and high to excellent α-selectivities.
摘要
首次发展了一种高效的 N-杂环卡宾催化 2-硝基半乳糖醛酸酯与醇和苯酚的糖苷化反应。可以以良好到优秀的收率和高到优秀的 α-选择性获得多种 1,2-顺式-2-硝基糖苷。
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