微藻作为高价值生物活性化合物的来源。

Microalgae as a source of high-value bioactive compounds.

作者信息

Bule Mohammed Hussen, Ahmed Ishtiaq, Maqbool Faheem, Bilal Muhammad, Iqbal Hafiz M N

机构信息

Department of Pharmacy, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.

School of Medical Science, Gold coast campus, Griffith University, Southport QLD 4222, Australia,

出版信息

Front Biosci (Schol Ed). 2018 Jan 1;10(2):197-216. doi: 10.2741/s509.

DOI:10.2741/s509

PMID:28930527

Abstract

Microalgae are one of the oldest microorganisms, that grow in various hostile environments, ranging from deserts to Antarctica. The microalgae sustain life in such harsh environments through generation of secondary metabolites. Microalgae biosynthesize a large number of diverse bioactive metabolites with activities on cancer, neurodegenerative diseases, and infectious diseases. Here, we highlight the bioactive compounds that are isolated from microalgae for the purpose of using them as food, and as chemicals in pharmaceutical industry as new agents with therapeutic benefits.

摘要

微藻是最古老的微生物之一，生长在从沙漠到南极洲的各种恶劣环境中。微藻通过产生次生代谢产物在如此恶劣的环境中维持生命。微藻生物合成大量具有抗癌、抗神经退行性疾病和抗感染疾病活性的多种生物活性代谢产物。在此，我们重点介绍从微藻中分离出的生物活性化合物，目的是将它们用作食品，以及用作制药行业的化学品，作为具有治疗益处的新型药物。