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Is it feasible to control pathogen infection by competitive binding of probiotics to the host?通过益生菌与宿主的竞争性结合来控制病原体感染是否可行？
Virulence. 2017 Nov 17;8(8):1502-1505. doi: 10.1080/21505594.2017.1382798. Epub 2017 Nov 9.
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Cell surface-associated aggregation-promoting factor from Lactobacillus gasseri SBT2055 facilitates host colonization and competitive exclusion of Campylobacter jejuni.来自格氏乳杆菌SBT2055的细胞表面相关聚集促进因子有助于宿主定殖并竞争性排除空肠弯曲菌。
Mol Microbiol. 2015 Nov;98(4):712-26. doi: 10.1111/mmi.13153. Epub 2015 Sep 15.
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Strain-specific probiotic (Lactobacillus helveticus) inhibition of Campylobacter jejuni invasion of human intestinal epithelial cells.特定菌株益生菌（瑞士乳杆菌）对空肠弯曲菌侵袭人肠上皮细胞的抑制作用。
FEMS Microbiol Lett. 2009 Nov;300(1):146-52. doi: 10.1111/j.1574-6968.2009.01781.x. Epub 2009 Sep 4.
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The role of probiotics in the inhibition of Campylobacter jejuni colonization and virulence attenuation.益生菌在抑制空肠弯曲菌定植及毒力减弱方面的作用。
Eur J Clin Microbiol Infect Dis. 2015 Aug;34(8):1503-13. doi: 10.1007/s10096-015-2392-z. Epub 2015 May 2.
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Evaluation of an avian-specific probiotic to reduce the colonization and shedding of Campylobacter jejuni in broilers.评估一种禽类专用益生菌对减少肉鸡空肠弯曲菌定植和排泄的作用。
Avian Dis. 1997 Oct-Dec;41(4):850-5.
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A Bifidobacterium-based synbiotic product to reduce the transmission of C. jejuni along the poultry food chain.一种基于双歧杆菌的合生产品，可减少空肠弯曲菌沿家禽食物链的传播。
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Int J Food Microbiol. 2010 Jul 31;141 Suppl 1:S98-108. doi: 10.1016/j.ijfoodmicro.2010.03.039. Epub 2010 Apr 8.
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Screening for lactic acid bacteria capable of inhibiting Campylobacter jejuni in in vitro simulations of the broiler chicken caecal environment.体外模拟肉鸡盲肠环境筛选能抑制空肠弯曲菌的乳酸菌。
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Probiotic bacteria are antagonistic to Salmonella enterica and Campylobacter jejuni and influence host lymphocyte responses in human microbiota-associated immunodeficient and immunocompetent mice.益生菌对肠炎沙门氏菌和空肠弯曲菌具有拮抗作用，并影响人类微生物群相关免疫缺陷和免疫健全小鼠的宿主淋巴细胞反应。
Mol Nutr Food Res. 2009 Mar;53(3):377-88. doi: 10.1002/mnfr.200800101.

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Homologous genes shared between probiotics and pathogens affect the adhesion of probiotics and exclusion of pathogens in the gut mucus of shrimp.益生菌和病原体之间共享的同源基因会影响益生菌在虾肠道黏液中的黏附以及对病原体的排斥。
Front Microbiol. 2023 Jun 14;14:1195137. doi: 10.3389/fmicb.2023.1195137. eCollection 2023.
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Modulatory Effects of Probiotics During Pathogenic Infections With Emphasis on Immune Regulation.益生菌在致病性感染期间的调节作用，重点是免疫调节。
Front Immunol. 2021 Apr 8;12:616713. doi: 10.3389/fimmu.2021.616713. eCollection 2021.
3
Dietary Nutrients, Proteomes, and Adhesion of Probiotic Lactobacilli to Mucin and Host Epithelial Cells.膳食营养素、蛋白质组以及益生菌乳酸杆菌与黏蛋白和宿主上皮细胞的黏附
Microorganisms. 2018 Aug 21;6(3):90. doi: 10.3390/microorganisms6030090.

本文引用的文献

1
Lactobacillus fermentum 3872 as a potential tool for combatting Campylobacter jejuni infections.发酵乳杆菌 3872 作为防治空肠弯曲菌感染的潜在工具。
Virulence. 2017 Nov 17;8(8):1753-1760. doi: 10.1080/21505594.2017.1362533. Epub 2017 Aug 25.
2
Cell surface-associated aggregation-promoting factor from Lactobacillus gasseri SBT2055 facilitates host colonization and competitive exclusion of Campylobacter jejuni.来自格氏乳杆菌SBT2055的细胞表面相关聚集促进因子有助于宿主定殖并竞争性排除空肠弯曲菌。
Mol Microbiol. 2015 Nov;98(4):712-26. doi: 10.1111/mmi.13153. Epub 2015 Sep 15.
3
Dynamics of brush border remodeling induced by enteropathogenic E. coli.肠致病性大肠杆菌诱导的刷状缘重塑动力学
Gut Microbes. 2014 Jul 1;5(4):504-16. doi: 10.4161/gmic.32084. Epub 2014 Jul 30.
4
Dancing to another tune-adhesive moonlighting proteins in bacteria.跳起别样的舞蹈——细菌中的黏着性 moonlighting 蛋白。
Biology (Basel). 2014 Mar 10;3(1):178-204. doi: 10.3390/biology3010178.
5
The E1 beta-subunit of pyruvate dehydrogenase is surface-expressed in Lactobacillus plantarum and binds fibronectin.丙酮酸脱氢酶 E1 亚基在植物乳杆菌中表面表达并结合纤连蛋白。
Microbiol Res. 2014 Feb-Mar;169(2-3):121-7. doi: 10.1016/j.micres.2013.07.013. Epub 2013 Sep 17.
6
Role of sortase-dependent pili of Bifidobacterium bifidum PRL2010 in modulating bacterium-host interactions.双歧杆菌 PRL2010 依赖 sortase 的菌毛在调节细菌-宿主相互作用中的作用。
Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11151-6. doi: 10.1073/pnas.1303897110. Epub 2013 Jun 17.
7
Anchorless surface associated glycolytic enzymes from Lactobacillus plantarum 299v bind to epithelial cells and extracellular matrix proteins.植物乳杆菌 299v 表面相关的无锚定糖酵解酶与上皮细胞和细胞外基质蛋白结合。
Microbiol Res. 2013 Jun 12;168(5):245-53. doi: 10.1016/j.micres.2013.01.003. Epub 2013 Feb 7.
8
Functional analysis of Lactobacillus rhamnosus GG pili in relation to adhesion and immunomodulatory interactions with intestinal epithelial cells.鼠李糖乳杆菌 GG 菌毛功能分析与其与肠道上皮细胞黏附和免疫调节相互作用的关系。
Appl Environ Microbiol. 2012 Jan;78(1):185-93. doi: 10.1128/AEM.06192-11. Epub 2011 Oct 21.
9
Protein-carbohydrate interactions between Lactobacillus salivarius and pig mucins.唾液乳杆菌与猪黏蛋白的蛋白-碳水化合物相互作用。
J Anim Sci. 2011 Oct;89(10):3125-31. doi: 10.2527/jas.2010-2996. Epub 2011 May 27.
10
Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor.细胞外基质与细胞信号：整合素、蛋白聚糖和生长因子受体的动态协作。
J Endocrinol. 2011 May;209(2):139-51. doi: 10.1530/JOE-10-0377. Epub 2011 Feb 9.

Is it feasible to control pathogen infection by competitive binding of probiotics to the host?

作者信息

Fukuda Kenji

机构信息

a Department of Animal and Food Hygiene , Obihiro University of Agriculture and Veterinary Medicine, Inada-cho , Obihiro , Hokkaido , Japan.

出版信息

Virulence. 2017 Nov 17;8(8):1502-1505. doi: 10.1080/21505594.2017.1382798. Epub 2017 Nov 9.

DOI:10.1080/21505594.2017.1382798
PMID:28934003
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5810465/
Abstract
摘要