• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

韩国生长猪口蹄疫二价疫苗单次接种最佳年龄的确定。

Determination of optimal age for single vaccination of growing pigs with foot-and-mouth disease bivalent vaccine in South Korea.

作者信息

Kim Ah-Young, Tark Dongseob, Kim Hyejin, Kim Jae-Seok, Lee Jung-Min, Kwon Minhee, Bae Soohyun, Kim Byounghan, Ko Young-Joon

机构信息

Center for FMD Vaccine Research, Animal and Plant Quarantine Agency, Gimcheon, Gyeonsangbuk-do 39660, Republic of Korea.

Korea Zoonosis Research Institute, Chonbuk National University, Iksan, Jeollabuk-do 54531, Republic of Korea.

出版信息

J Vet Med Sci. 2017 Nov 10;79(11):1822-1825. doi: 10.1292/jvms.17-0338. Epub 2017 Sep 22.

DOI:10.1292/jvms.17-0338
PMID:28943596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5709559/
Abstract

In South Korea, pigs were vaccinated once between 8 and 12 weeks of age because of the injection-site granulomas. Therefore this study was performed to determine the optimal age for single vaccination of growing pigs with the currently used type O FMD vaccine. With 498 pigs divided into four groups, seroprevalence of the antibody was analyzed with enzyme-linked immunosorbent assay. Although double vaccination is necessary to completely protect growing pigs from FMD virus infection with the current vaccine, the age of 8 weeks can be considered as the optimal age for piglet vaccination if the booster injection is unavailable.

摘要

在韩国，由于注射部位肉芽肿问题，猪在8至12周龄时接种一次疫苗。因此，本研究旨在确定使用当前O型口蹄疫疫苗对生长猪进行单次接种的最佳年龄。将498头猪分为四组，采用酶联免疫吸附测定法分析抗体血清阳性率。尽管使用当前疫苗对生长猪进行完全保护免受口蹄疫病毒感染需要进行两次接种，但如果无法进行加强注射，8周龄可被视为仔猪接种疫苗的最佳年龄。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8505/5709559/ce6cb3693ea7/jvms-79-1822-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8505/5709559/395d051c98ca/jvms-79-1822-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8505/5709559/ce6cb3693ea7/jvms-79-1822-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8505/5709559/395d051c98ca/jvms-79-1822-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8505/5709559/ce6cb3693ea7/jvms-79-1822-g002.jpg

相似文献

1
Determination of optimal age for single vaccination of growing pigs with foot-and-mouth disease bivalent vaccine in South Korea.韩国生长猪口蹄疫二价疫苗单次接种最佳年龄的确定。
J Vet Med Sci. 2017 Nov 10;79(11):1822-1825. doi: 10.1292/jvms.17-0338. Epub 2017 Sep 22.
2
Serological responses after vaccination of growing pigs with foot-and-mouth disease trivalent (type O, A and Asia1) vaccine.猪口蹄疫三价（O 型、A型和 Asia1 型）疫苗接种后血清学反应。
Vet Microbiol. 2013 Jun 28;164(3-4):239-45. doi: 10.1016/j.vetmic.2013.02.012. Epub 2013 Feb 24.
3
Control of type O foot-and-mouth disease by vaccination in Korea, 2014-2015.2014 - 2015年韩国通过疫苗接种控制O型口蹄疫
J Vet Sci. 2018 Mar 31;19(2):271-279. doi: 10.4142/jvs.2018.19.2.271.
4
New foot-and-mouth disease vaccine, O JC-R, induce complete protection to pigs against SEA topotype viruses occurred in South Korea, 2014-2015.新型口蹄疫疫苗O JC-R可使猪对2014 - 2015年在韩国出现的东南亚型病毒产生完全保护。
J Vet Sci. 2019 Jul;20(4):e42. doi: 10.4142/jvs.2019.20.e42.
5
Increased humoral antibody response of foot-and-mouth disease virus vaccine in growing pigs pre-treated with poly-γ-glutamic acid.用聚γ-谷氨酸预处理的生长猪对口蹄疫病毒疫苗的体液抗体反应增强。
J Vet Sci. 2016 Jun 30;17(2):253-6. doi: 10.4142/jvs.2016.17.2.253.
6
Improved foot-and-mouth disease vaccine, O TWN-R, protects pigs against SEA topotype virus occurred in South Korea.改进型口蹄疫疫苗 O TWN-R 可保护猪免受在韩国发生的 SEA 拓扑型病毒的侵害。
Vet Microbiol. 2019 Sep;236:108374. doi: 10.1016/j.vetmic.2019.07.026. Epub 2019 Jul 25.
7
Immune responses of pigs to commercialized emulsion FMD vaccines and live virus challenge.猪对商业化口蹄疫乳化疫苗和活病毒攻毒的免疫反应。
Vaccine. 2007 May 30;25(22):4464-9. doi: 10.1016/j.vaccine.2007.03.019. Epub 2007 Mar 28.
8
Serological and mucosal immune responses after vaccination and infection with FMDV in pigs.猪接种口蹄疫病毒疫苗及感染后血清学和黏膜免疫反应
Vaccine. 2007 Jan 22;25(6):1043-54. doi: 10.1016/j.vaccine.2006.09.066. Epub 2006 Oct 9.
9
Effects of germanium biotite supplement on immune responses of vaccinated mini-pigs to foot-and-mouth disease virus challenge.补充锗云母对接种疫苗的小型猪对口蹄疫病毒攻击的免疫反应的影响。
Immunol Invest. 2015;44(1):101-12. doi: 10.3109/08820139.2014.938164. Epub 2014 Jul 24.
10
Immune responses in pigs and cattle vaccinated with half-volume foot-and-mouth disease vaccine.用半剂量口蹄疫疫苗接种的猪和牛的免疫反应。
J Vet Sci. 2017 Aug 31;18(S1):323-331. doi: 10.4142/jvs.2017.18.S1.323.

引用本文的文献

1
Vaccination Failures in Pigs-The Impact of Chosen Factors on the Immunisation Efficacy.猪的疫苗接种失败——所选因素对免疫效果的影响
Vaccines (Basel). 2023 Jan 19;11(2):230. doi: 10.3390/vaccines11020230.
2
Application of Heparin Affinity Chromatography to Produce a Differential Vaccine without Eliciting Antibodies against the Nonstructural Proteins of the Serotype O Foot-and-Mouth Disease Viruses.肝素亲和层析在制备 O 型口蹄疫病毒非结构蛋白无抗体诱导差减疫苗中的应用
Viruses. 2020 Dec 7;12(12):1405. doi: 10.3390/v12121405.
3
Evaluation and optimization of a conventional SPCE for FMD post-vaccination monitoring.

本文引用的文献

1
Challenges of Generating and Maintaining Protective Vaccine-Induced Immune Responses for Foot-and-Mouth Disease Virus in Pigs.在猪中产生和维持针对口蹄疫病毒的保护性疫苗诱导免疫反应的挑战
Front Vet Sci. 2016 Nov 30;3:102. doi: 10.3389/fvets.2016.00102. eCollection 2016.
2
Proper Timing of Foot-and-Mouth Disease Vaccination of Piglets with Maternally Derived Antibodies Will Maximize Expected Protection Levels.仔猪母源抗体对口蹄疫疫苗接种的适时性将最大限度地提高预期保护水平。
Front Vet Sci. 2016 Jun 30;3:52. doi: 10.3389/fvets.2016.00052. eCollection 2016.
3
Control of foot-and-mouth disease during 2010-2011 epidemic, South Korea.
用于口蹄疫疫苗接种后监测的传统丝网印刷碳电极的评估与优化
BMC Vet Res. 2018 Nov 28;14(1):371. doi: 10.1186/s12917-018-1686-7.
4
Genetic identification and serological evaluation of commercial inactivated foot-and-mouth disease virus vaccine in pigs.猪用商业性灭活口蹄疫病毒疫苗的基因鉴定及血清学评价
Clin Exp Vaccine Res. 2018 Jul;7(2):139-144. doi: 10.7774/cevr.2018.7.2.139. Epub 2018 Jul 31.
韩国 2010-2011 年口蹄疫疫情控制情况。
Emerg Infect Dis. 2013 Apr;19(4):655-9. doi: 10.3201/eid1904.121320.
4
Serological responses after vaccination of growing pigs with foot-and-mouth disease trivalent (type O, A and Asia1) vaccine.猪口蹄疫三价（O 型、A型和 Asia1 型）疫苗接种后血清学反应。
Vet Microbiol. 2013 Jun 28;164(3-4):239-45. doi: 10.1016/j.vetmic.2013.02.012. Epub 2013 Feb 24.
5
Efficacy of foot-and-mouth disease vaccine in pigs with single dose immunization.口蹄疫疫苗对猪单剂量免疫的效果
Vaccine. 2003 May 16;21(17-18):1807-10. doi: 10.1016/s0264-410x(03)00030-6.
6
FMD vaccines.口蹄疫疫苗
Virus Res. 2003 Jan;91(1):81-99. doi: 10.1016/s0168-1702(02)00261-7.
7
A solid-phase blocking ELISA for detection of type O foot-and-mouth disease virus antibodies suitable for mass serology.一种用于检测O型口蹄疫病毒抗体的固相阻断ELISA，适用于大规模血清学检测。
J Virol Methods. 2003 Jan;107(1):89-98. doi: 10.1016/s0166-0934(02)00196-9.
8
Optimisation of the immune response to foot-and-mouth disease vaccines.口蹄疫疫苗免疫反应的优化
Vaccine. 1999 Mar 26;17(13-14):1767-71. doi: 10.1016/s0264-410x(98)00444-7.
9
International bank for foot-and-mouth disease vaccine: assessment of Montanide ISA 25 and ISA 206, two commercially available oil adjuvants.口蹄疫疫苗国际库：两种市售油佐剂Montanide ISA 25和ISA 206的评估
Vaccine. 1996 Sep;14(13):1187-98. doi: 10.1016/s0264-410x(96)00055-2.