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Neuropsychiatr Dis Treat. 2016 Dec 8;12:3119-3128. doi: 10.2147/NDT.S116148. eCollection 2016.
2
Rates and characteristics of elderly suicide in China, 2013-14.2013 - 2014年中国老年人自杀率及特征
J Affect Disord. 2016 Dec;206:273-279. doi: 10.1016/j.jad.2016.09.003. Epub 2016 Sep 13.
3
Prevalence of schizophrenia in China between 1990 and 2010.1990年至2010年间中国精神分裂症的患病率。
J Glob Health. 2015 Jun;5(1):010410. doi: 10.7189/jogh.05.010410.
4
Prevalence of suicidal ideation and suicide attempts in the general population of China: A meta-analysis.中国普通人群中自杀意念和自杀未遂的患病率:一项荟萃分析。
Int J Psychiatry Med. 2015;49(4):296-308. doi: 10.1177/0091217415589306. Epub 2015 Jun 9.
5
Risk factors for suicide in schizophrenia: systematic review and clinical recommendations.精神分裂症患者自杀的危险因素:系统评价与临床建议
Acta Psychiatr Scand. 2014 Dec;130(6):418-26. doi: 10.1111/acps.12332. Epub 2014 Sep 18.
6
Prevalence of autism spectrum disorders among children in China: a systematic review.中国儿童自闭症谱系障碍的患病率:一项系统综述。
Shanghai Arch Psychiatry. 2013 Apr;25(2):70-80. doi: 10.3969/j.issn.1002-0829.2013.02.003.
7
The prevalence of schizophrenia in mainland China: evidence from epidemiological surveys.中国大陆精神分裂症的流行情况:来自流行病学调查的证据。
Acta Psychiatr Scand. 2014 Oct;130(4):244-56. doi: 10.1111/acps.12296. Epub 2014 Jun 11.
8
Suicide rates in China from 2002 to 2011: an update.2002年至2011年中国的自杀率:最新情况
Soc Psychiatry Psychiatr Epidemiol. 2014 Jun;49(6):929-41. doi: 10.1007/s00127-013-0789-5. Epub 2013 Nov 16.
9
A systematic review and meta-regression analysis of aggression during the first episode of psychosis.精神病首次发作期间的攻击性:系统评价和荟萃回归分析。
Acta Psychiatr Scand. 2013 Dec;128(6):413-21. doi: 10.1111/acps.12113. Epub 2013 Mar 22.
10
Association of the 5HTR2A gene with suicidal behavior: case-control study and updated meta-analysis.5-羟色胺 2A 受体基因与自杀行为的关联:病例对照研究和更新的荟萃分析。
BMC Psychiatry. 2013 Jan 12;13:25. doi: 10.1186/1471-244X-13-25.

中国精神分裂症患者自杀相关行为的综合荟萃分析。

Suicide-related behaviours in schizophrenia in China: a comprehensive meta-analysis.

机构信息

Faculty of Health Sciences,University of Macau,Macao SAR,China.

Guangdong Mental Health Center, Guangdong General Hospital & Guangdong Academy of Medical Sciences,Guangdong Province,China.

出版信息

Epidemiol Psychiatr Sci. 2019 Jun;28(3):290-299. doi: 10.1017/S2045796017000476. Epub 2017 Sep 25.

DOI:10.1017/S2045796017000476
PMID:28944747
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6998905/
Abstract

AIMS

Suicide-related behaviours are common in schizophrenia and are significantly associated with premature death. The objective of this meta-analysis study was to estimate the pooled prevalence of suicide-related behaviours in schizophrenia patients in China.

METHODS

The relevant literature was searched systematically via the relevant electronic databases (PubMed, Embase, PsycINFO, Chinese National Knowledge Infrastructure, Wanfang Databases and Chinese Biological Medical Literature Database) from their inception until 14 September 2016. Only original studies that reported the prevalence of suicide-related behaviours including suicidal ideation (SI), suicide plan, suicide attempt (SA) and completed suicide were selected.

RESULTS

Nineteen articles met the inclusion criteria and were analysed. The pooled lifetime prevalence of SI and SA were 25.8% (95% CI 14.7-41.1%) and 14.6% (95% CI 9.1-22.8%), respectively. The 1-month prevalence of SI was 22.0% (95% CI 18.2-26.4%). Subgroup analyses of lifetime SI and SA showed that gender, sample size, survey year, study location and source of patients have no significant mediating effects on the results.

CONCLUSIONS

Suicide-related behaviours are common in Chinese schizophrenia patients. Due to the high mortality risk, regular screening and effective suicide prevention programmes are warranted.

摘要

目的

自杀相关行为在精神分裂症中很常见,与过早死亡显著相关。本荟萃分析旨在评估中国精神分裂症患者自杀相关行为的总体发生率。

方法

通过相关电子数据库(PubMed、Embase、PsycINFO、中国国家知识基础设施、万方数据库和中国生物医学文献数据库)系统地检索相关文献,检索时间截至 2016 年 9 月 14 日。仅纳入报告自杀相关行为(包括自杀意念、自杀计划、自杀未遂和自杀完成)发生率的原始研究。

结果

符合纳入标准的文献共 19 篇,进行荟萃分析。精神分裂症患者终生自杀意念和自杀未遂的发生率分别为 25.8%(95%CI 14.7-41.1%)和 14.6%(95%CI 9.1-22.8%)。1 个月时自杀意念的发生率为 22.0%(95%CI 18.2-26.4%)。亚组分析显示,性别、样本量、调查年份、研究地点和患者来源对终生自杀意念和自杀未遂的发生率无显著影响。

结论

自杀相关行为在我国精神分裂症患者中很常见。由于其高死亡率,需要定期进行筛查,并实施有效的自杀预防计划。