Alcorn Tara, Hart Elise, Smith Ashleigh E, Feuerriegel Daniel, Stephan Blossom C M, Siervo Mario, Keage Hannah A D
a School of Psychology, Social Work and Social Policy , University of South Australia , Australia.
b Alliance for Research in Exercise Nutrition and Activity (ARENA) , The Sansom Institute for Health Research, Health Sciences, University of South Australia , Australia.
Appl Neuropsychol Adult. 2019 Mar-Apr;26(2):186-199. doi: 10.1080/23279095.2017.1363039. Epub 2017 Sep 25.
This review aimed to systematically evaluate associations between the Metabolic Syndrome and domain specific cognitive performance from cross-sectional studies. PsycINFO and Medline were searched on 12 January 2017 with the terms "Metabolic Syndrome" and "cogni*." A total of 973 articles were identified, with 26 meeting inclusion criteria. Individuals with Metabolic Syndrome were consistently reported to have poorer performance on executive function tasks that were not adaptations of the verbal fluency task, including the Stockings of Cambridge test, Color-Word Inference Test and Frontal Assessment Battery; findings from adaptations of the verbal fluency test showed less consistent results. Associations with performance in attention/working memory/information processing, memory, language, and construction/motor performance domains were mixed. All studies reporting on perception showed nonsignificant results. Non-language based executive function tasks appear to be the most sensitive tests of Metabolic Syndrome, and hold promise as a cognitive screen and for the tracking of interventions in this group.
本综述旨在通过横断面研究系统评估代谢综合征与特定领域认知表现之间的关联。于2017年1月12日在PsycINFO和Medline数据库中检索了“代谢综合征”和“认知*”等术语。共识别出973篇文章，其中26篇符合纳入标准。一直有报告称，患有代谢综合征的个体在非言语流畅性任务改编版的执行功能任务上表现较差，包括剑桥长袜测试、颜色-文字推理测试和额叶评估量表；言语流畅性测试改编版的研究结果则不太一致。与注意力/工作记忆/信息处理、记忆、语言以及构建/运动表现领域的表现之间的关联参差不齐。所有关于感知的研究结果均无统计学意义。基于非语言的执行功能任务似乎是代谢综合征最敏感的测试，有望作为认知筛查工具以及用于跟踪该群体的干预措施。
