Derbyshire E
Nutritional Insight Ltd, Surrey, UK.
J Lipids. 2017;2017:6285218. doi: 10.1155/2017/6285218. Epub 2017 Aug 30.
Attention deficit hyperactivity disorder (ADHD) is a debilitating behavioural disorder affecting daily ability to function, learn, and interact with peers. This publication assesses the role of omega-3/6 fatty acids in the treatment and management of ADHD.
A systematic review of 16 randomised controlled trials was undertaken. Trials included a total of 1,514 children and young people with ADHD who were allocated to take an omega-3/6 intervention, or a placebo.
Of the studies identified, 13 reported favourable benefits on ADHD symptoms including improvements in hyperactivity, impulsivity, attention, visual learning, word reading, and working/short-term memory. Four studies used supplements containing a 9 : 3 : 1 ratio of eicosapentaenoic acid : docosahexaenoic acid : gamma linolenic acid which appeared effective at improving erythrocyte levels. Supplementation with this ratio of fatty acids also showed promise as an adjunctive therapy to traditional medications, lowering the dose and improving the compliance with medications such as methylphenidate.
ADHD is a frequent and debilitating childhood condition. Given disparaging feelings towards psychostimulant medications, omega-3/6 fatty acids offer great promise as a suitable adjunctive therapy for ADHD.
注意力缺陷多动障碍（ADHD）是一种使人衰弱的行为障碍，会影响日常功能、学习以及与同伴互动的能力。本出版物评估了ω-3/6脂肪酸在ADHD治疗和管理中的作用。
对16项随机对照试验进行了系统评价。这些试验共纳入了1514名患有ADHD的儿童和青少年，他们被分配接受ω-3/6干预或安慰剂。
在已确定的研究中，13项报告了对ADHD症状有有利影响，包括多动、冲动、注意力、视觉学习、单词阅读以及工作/短期记忆方面的改善。四项研究使用了含有二十碳五烯酸∶二十二碳六烯酸∶γ-亚麻酸比例为9∶3∶1的补充剂，这似乎对提高红细胞水平有效。补充这种脂肪酸比例作为传统药物的辅助治疗也显示出前景，可降低剂量并提高对诸如哌甲酯等药物的依从性。
ADHD是一种常见且使人衰弱的儿童疾病。鉴于对精神兴奋剂药物的负面看法，ω-3/6脂肪酸作为ADHD合适的辅助治疗方法具有很大前景。
