Elgendi Mohamed
Department of Obstetrics & Gynecology, University of British Columbia, Vancouver, BC V6Z 2K5, Canada.
Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Bioengineering (Basel). 2016 Sep 22;3(4):22. doi: 10.3390/bioengineering3040022.
Biomedical signals carry valuable physiological information and many researchers have difficulty interpreting and analyzing long-term, one-dimensional, quasi-periodic biomedical signals. Traditionally, biomedical signals are analyzed and visualized using periodogram, spectrogram, and wavelet methods. However, these methods do not offer an informative visualization of main events within the processed signal. This paper attempts to provide an event-related framework to overcome the drawbacks of the traditional visualization methods and describe the main events within the biomedical signal in terms of duration and morphology. Electrocardiogram and photoplethysmogram signals are used in the analysis to demonstrate the differences between the traditional visualization methods, and their performance is compared against the proposed method, referred to as the "" in this paper. The proposed method is based on two event-related moving averages that visualizes the main time-domain events in the processed biomedical signals. The traditional visualization methods were unable to find dominant events in processed signals while the was able to visualize dominant events in signals in terms of duration and morphology. Moreover, -based detection algorithms succeeded with detecting main events in different biomedical signals with a sensitivity and positive predictivity >95%. The output of the captured unique patterns and signatures of physiological events, which could be used to visualize and identify abnormal waveforms in any quasi-periodic signal.
生物医学信号承载着有价值的生理信息,许多研究人员在解释和分析长期的、一维的、准周期性的生物医学信号时存在困难。传统上,生物医学信号是使用周期图、频谱图和小波方法进行分析和可视化的。然而,这些方法无法对处理后的信号中的主要事件进行有效的可视化。本文试图提供一个与事件相关的框架,以克服传统可视化方法的缺点,并从持续时间和形态方面描述生物医学信号中的主要事件。在分析中使用了心电图和光电容积脉搏波信号来展示传统可视化方法之间的差异,并将它们的性能与本文提出的称为“ ”的方法进行比较。所提出的方法基于两个与事件相关的移动平均值,用于可视化处理后的生物医学信号中的主要时域事件。传统的可视化方法无法在处理后的信号中找到主导事件,而“ ”能够从持续时间和形态方面可视化信号中的主导事件。此外,基于“ ”的检测算法成功地检测出不同生物医学信号中的主要事件,灵敏度和阳性预测值均大于95%。“ ”的输出捕捉到了生理事件的独特模式和特征,可用于可视化和识别任何准周期性信号中的异常波形。