Elgendi Mohamed, Fletcher Richard, Liang Yongbo, Howard Newton, Lovell Nigel H, Abbott Derek, Lim Kenneth, Ward Rabab
1School of Electrical and Computer Engineering, University of British Columbia, Vancouver, Canada.
2Department of Obstetrics & Gynecology, University of British Columbia, Vancouver, Canada.
NPJ Digit Med. 2019 Jun 26;2:60. doi: 10.1038/s41746-019-0136-7. eCollection 2019.
The measurement of blood pressure (BP) is critical to the treatment and management of many medical conditions. High blood pressure is associated with many chronic disease conditions, and is a major source of mortality and morbidity around the world. For outpatient care as well as general health monitoring, there is great interest in being able to accurately and frequently measure BP outside of a clinical setting, using mobile or wearable devices. One possible solution is photoplethysmography (PPG), which is most commonly used in pulse oximetry in clinical settings for measuring oxygen saturation. PPG technology is becoming more readily available, inexpensive, convenient, and easily integrated into portable devices. Recent advances include the development of smartphones and wearable devices that collect pulse oximeter signals. In this article, we review (i) the state-of-the-art and the literature related to PPG signals collected by pulse oximeters, (ii) various theoretical approaches that have been adopted in PPG BP measurement studies, and (iii) the potential of PPG measurement devices as a wearable application. Past studies on changes in PPG signals and BP are highlighted, and the correlation between PPG signals and BP are discussed. We also review the combined use of features extracted from PPG and other physiological signals in estimating BP. Although the technology is not yet mature, it is anticipated that in the near future, accurate, continuous BP measurements may be available from mobile and wearable devices given their vast potential.
血压测量对于多种病症的治疗和管理至关重要。高血压与许多慢性疾病相关,是全球死亡率和发病率的主要来源。对于门诊护理以及一般健康监测而言,人们非常希望能够使用移动或可穿戴设备在临床环境之外准确且频繁地测量血压。一种可能的解决方案是光电容积脉搏波描记法(PPG),它在临床环境中最常用于脉搏血氧测定以测量血氧饱和度。PPG技术正变得越来越容易获得、价格低廉、方便且易于集成到便携式设备中。最近的进展包括开发能够收集脉搏血氧仪信号的智能手机和可穿戴设备。在本文中,我们回顾:(i)与脉搏血氧仪收集的PPG信号相关的最新技术水平和文献;(ii)PPG血压测量研究中采用的各种理论方法;以及(iii)PPG测量设备作为可穿戴应用的潜力。重点介绍了过去关于PPG信号和血压变化的研究,并讨论了PPG信号与血压之间的相关性。我们还回顾了在估计血压时从PPG和其他生理信号中提取的特征的联合使用。尽管该技术尚未成熟,但鉴于其巨大潜力,预计在不久的将来,移动和可穿戴设备可能会提供准确、连续的血压测量。