5号染色体部分三体与精神分裂症共分离。
Partial trisomy chromosome 5 cosegregating with schizophrenia.
作者信息
Bassett A S, McGillivray B C, Jones B D, Pantzar J T
机构信息
Department of Psychiatry, Health Sciences Centre Hospital, University of British Columbia, Vancouver, Canada.
出版信息
Lancet. 1988 Apr 9;1(8589):799-801. doi: 10.1016/s0140-6736(88)91660-1.
Abstract
Schizophrenia was associated with a distinct autosomal abnormality in two related mildly dysmorphic individuals. The finding of cosegregation of schizophrenia and a partial trisomy of chromosome 5 in the family suggests a potential location of a gene or genes linked to schizophrenia.
摘要
在两名相关的轻度畸形个体中，精神分裂症与一种明显的常染色体异常有关。该家族中精神分裂症与5号染色体部分三体的共分离现象表明，存在一个或多个与精神分裂症相关基因的潜在定位。
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