Department of Psychosomatic Medicine and Psychotherapy, University Hospital Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany.
University Clinic Hamburg-Eppendorf, Clinic and Policlinic for Psychiatry and Psychotherapy, Martinistraße 52, 20246 Hamburg, Germany.
Nutrients. 2017 Sep 27;9(10):1068. doi: 10.3390/nu9101068.
Patients with binge eating disorder (BED) suffer from regular food binges with loss of control. This may be due to dysfunctional approach vs. avoidance tendencies towards food in BED. We applied an approach-avoidance task (AAT), in which = 24 patients with obesity and active BED (OB-BED), = 32 patients with obesity without current BED (OB), and = 25 healthy controls (CO) either approached ("pulled") or avoided ("pushed") high (HC) vs. low calorie (LC) food pictures. We tested the hypothesis that OB-BED patients would show an approach bias (measured as different response times RT) towards HC food compared to the other groups. While there was no main effect for group or direction of movement, a significant main effect for calorie ( < 0.001; RT for HC significantly slower than for LC) was found. Repeated measures ANOVA (rm-ANOVA) for comparison of OB-BED vs. OB vs. CO revealed a significant three-fold interaction group × direction × calorie ( = 0.02). Against our hypothesis, the OB-BED group showed an avoidance bias for LC. In explicit ratings, OB-BED reported a significantly reduced urge to consume LC food compared to the OB group. Similar to OB-BED, CO also showed an avoidance bias for LC. The implications of our results are discussed and future directions in this field of research are presented.
患有暴食症（BED）的患者会经常出现无法控制的暴食行为。这可能是由于 BED 患者对食物的趋近-回避倾向出现了功能障碍。我们应用了趋近-回避任务（AAT），其中包括 24 名肥胖且患有活跃暴食症的患者（OB-BED）、32 名肥胖但没有当前暴食症的患者（OB）和 25 名健康对照者（CO），他们要么趋近（“拉”）要么回避（“推”）高热量（HC）与低热量（LC）食物图片。我们检验了 OB-BED 患者相对于其他两组对 HC 食物表现出趋近偏向（通过不同的反应时 RT 来衡量）的假设。虽然组间或运动方向没有主效应，但卡路里有显著的主效应（<0.001；HC 的 RT 明显慢于 LC）。OB-BED 与 OB 与 CO 进行比较的重复测量方差分析（rm-ANOVA）显示，组间×方向×卡路里的三重交互作用显著（=0.02）。与我们的假设相反，OB-BED 组对 LC 表现出回避偏向。在明确的评分中，OB-BED 报告的对 LC 食物的消费欲望明显低于 OB 组。与 OB-BED 相似，CO 对 LC 也表现出回避偏向。我们的结果的影响将进行讨论，并提出该研究领域的未来方向。
