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银屑病患者瘙痒与临床变量之间的关系。

The relationship between pruritus and clinical variables in patients with psoriasis.

作者信息

Bahali Anil Gulsel, Onsun Nahide, Su Ozlem, Ozkaya Dilek Biyik, Dizman Didem, Topukcu Bugce, Uysal Omer

机构信息

Department of Dermatology, Medical Faculty, Bezmialem Vakif University - Istanbul, Turquia.

Department of Dermatology, Ardahan State Hospital - Ardahan, Turkey.

出版信息

An Bras Dermatol. 2017 Jul-Aug;92(4):470-473. doi: 10.1590/abd1806-4841.20175402.

DOI:10.1590/abd1806-4841.20175402
PMID:28954093
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5595591/
Abstract

BACKGROUND

: Pruritus is the most commonly occurring subjective symptom of dermatological disease. Published data on both prevalence and intensity of pruritus in psoriasis is limited.

OBJECTIVE

: In this study we aimed to investigate the prevalence of pruritus and its relation with psoriasis area severity index, body mass index and presence of systemic disease in patients with psoriasis.

METHODS

: We analyzed data of psoriatic patients diagnosed in our psoriasis outpatient clinic between March 2013 and June 2014 collected retrospectively from PSR-TR registration system.

RESULTS

: In total, 880 patients were analyzed. Pruritus was more prominent in female patients. This difference was statistically significant. No significant associations were found between age of patients, clinical type of disease and pruritus. The itching was more common in patients with higher body mass index. Presence of pruritus was correlated significantly with severity of psoriasis. Five hundred and sixty of 880 patients had no systemic disease. The presence of pruritus was not related with presence of systemic disease. Existence of systemic disease with psoriasis has minimal effect on pruritus.

STUDY LIMITATIONS

: We did not evaluate intensity of pruritus.

CONCLUSIONS

: Pruritus is not mentioned within the classical symptoms of psoriasis. Pruritus in psoriasis is a very unpleasant symptom with great potential to impair patient's quality of life and may exacerbate psoriasis as a Koebner phenomenon.

摘要

背景

瘙痒是皮肤病最常见的主观症状。关于银屑病瘙痒发生率和严重程度的已发表数据有限。

目的

在本研究中,我们旨在调查银屑病患者瘙痒的发生率及其与银屑病面积和严重程度指数、体重指数以及系统性疾病的关系。

方法

我们分析了2013年3月至2014年6月期间在我们银屑病门诊诊断的银屑病患者的数据,这些数据是从PSR-TR登记系统中回顾性收集的。

结果

总共分析了880例患者。瘙痒在女性患者中更为突出。这种差异具有统计学意义。在患者年龄、疾病临床类型和瘙痒之间未发现显著关联。瘙痒在体重指数较高的患者中更常见。瘙痒的存在与银屑病的严重程度显著相关。880例患者中有560例没有系统性疾病。瘙痒的存在与系统性疾病的存在无关。银屑病合并系统性疾病对瘙痒的影响最小。

研究局限性

我们没有评估瘙痒的严重程度。

结论

瘙痒在银屑病的经典症状中未被提及。银屑病中的瘙痒是一种非常令人不适的症状,极有可能损害患者的生活质量,并可能作为同形反应加重银屑病。

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Pruritus in psoriasis: a study of personality traits, depression and anxiety.银屑病瘙痒症:一项关于人格特质、抑郁和焦虑的研究。
Acta Derm Venereol. 2015 Apr;95(4):439-43. doi: 10.2340/00015555-1975.
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Pruritus in chronic plaque psoriasis: a questionnaire-based study of 230 Italian patients.慢性斑块状银屑病的瘙痒:一项基于问卷调查的对230例意大利患者的研究。
Acta Dermatovenerol Croat. 2014;22(2):122-8.
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9
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